ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Proline derivatives Z-HYP-OME

Z-HYP-OME

Z-HYP-OME Basic information
Product Name:Z-HYP-OME
Synonyms:N-Cbz-trans-4-hydroxy-L-proline methyl ester;Z-O-tert-Butyl-L-4-hydroxyproline;(2S,4R)-1-(Benzyloxycarbonyl)-2-(methoxycarbonyl)-4-hydroxypyrrolidine;(2S,4R)-1-Benzyloxycarbonyl-4-hydroxypyrrolidin-2-carboxylic acid methyl ester;1-Benzyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate;N-(Benzyloxycarbonyl)-4-hydroxyproline methyl ester;(2S,4R)-1-benzyl 2-Methyl 4-hydro×ypyrrolidine-1,2-dicarbo×ylate;Cbz-L-Hyp-OMe
CAS:64187-48-0
MF:C14H17NO5
MW:279.29
EINECS:613-498-5
Product Categories:
Mol File:64187-48-0.mol
Z-HYP-OME Structure
Z-HYP-OME Chemical Properties
Boiling point 422.8±45.0 °C(Predicted)
density 1.313
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka14.25±0.40(Predicted)
form viscous liquid
color Pale yellow
Safety Information
WGK Germany 3
HS Code 2933.99.8290
MSDS Information
ProviderLanguage
SigmaAldrich English
Z-HYP-OME Usage And Synthesis
Chemical PropertiesLight yellowish liquid
UsesN-(Benzyloxycarbonyl)-4-hydroxyproline Methyl Ester, can be used as an intermediate in the synthesis of various pharmaceutical and biologically active compounds. It is used in the synthesis of Doripenem (D534800), an Antibacterial agent.
Z-HYP-OME Preparation Products And Raw materials
Preparation Products2-PyrrolidineMethanol, 4-hydroxy-, hydrochloride (1:1), (2S,4R)--->N-BOC-cis-4-fluoro-L-proline-->Carbamic acid, [[(2S,4R)-4-hydroxy-2-pyrrolidinyl]methyl]-, 1,1-dimethylethyl-->Carbamic acid, [(3S,5S)-5-(hydroxymethyl)-3-pyrrolidinyl]-, 1,1-dimethylethyl-->3-Pyrrolidinol, 5-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, (3R,5S)--->Z-TRANS-4-HYDROXY-L-PROLINOL
Z-TRANS-4-HYDROXY-L-PROLINOL N-Cbz-Hydroxy-L-proline (R)-1-CBZ-3-PYRROLIDINOL (S)-(+)-2-(METHOXYMETHYL)PYRROLIDINE N-Carbobenzoxy-L-homoserine Z-L-PROLINE (2S)-1,2-PYRROLIDINEDICARBOXYLIC ACID-1-ETHYL-2-METHYL ESTER (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE Methyl (S)-(+)-3-hydroxybutyrate Z-HYP-OME L-ZHPROMSME (S)-(+)-1-Methyl-3-pyrrolidinol 1-CBZ-4(R)-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID ETHYL ESTER Z-MEALA-OH Z-SAR-OH 1-Methyl-3-pyrrolidinol 5-(Z-AMINO)-1-PENTANOL N-N-bis(2-hydroxyethyl)formamide
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