(S)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol

(S)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol Basic information
Product Name:(S)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol
Synonyms:(S)-(-)-ɑ,ɑ-Diphenylprolinol, 98%;(S)-2-(Hydroxydiphenylmethyl)pyrrolidine;alpha,alpha-diphenyl-L-proline;(S)-α,α-Diphenyl-2-pyrrolidinemethanol, (S)-2-(Diphenylhydroxymethyl)pyrrolidine;(S)-(-)-2-(Diphenylhydroxymethyl)pyrrolidine, α,α-Diphenyl-L-prolinol;(S)-(-)-Alpha,alpha-diphenyl-2-pyrrolidin emethanol, 99+%;(2S)-α,α-Diphenyl-2-pyrrolidinemethanol;(2S)-α,α-Diphenyl-2α-pyrrolidinemethanol
CAS:112068-01-6
MF:C17H19NO
MW:253.34
EINECS:601-153-1
Product Categories:Peptide;Asymmetric Synthesis;Chiral Building Blocks;Simple Alcohols (Chiral);Synthetic Organic Chemistry;CHIRAL CHEMICALS;chiral;Chiral Reagent;Chiral Reagents;Benzenes;Chiral chemicals;Pharmaceutical intermediate;Chiral Nitrogen
Mol File:112068-01-6.mol
(S)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol Structure
(S)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol Chemical Properties
Melting point 77-80 °C(lit.)
alpha -59 º (c=3, methanol 25 ºC)
Boiling point 396.54°C (rough estimate)
density 1.0078 (rough estimate)
refractive index -66.5 ° (C=3, CHCl3)
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in chloroform.
pka13.15±0.29(Predicted)
form powder
color white to off white ., crystal
optical activity[α]20/D 67°, c = 3 in chloroform
Merck 14,155
BRN 17103
InChIKeyOGCGXUGBDJGFFY-INIZCTEOSA-N
CAS DataBase Reference112068-01-6(CAS DataBase Reference)
NIST Chemistry ReferenceS-(-)-1,1-diphenylprolinol(112068-01-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39-24/25-36
WGK Germany 3
10-34
TSCA No
HS Code 29339900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
(S)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol Usage And Synthesis
Chemical Propertieswhite to beige crystals or crystalline powder
Usessuzuki reaction
Uses(S)-(-)-alpha,alpha-Diphenylprolinol is used to prepare the corresponding oxazaborolidines for the borane-mediated asymmetric reduction of ketones.
General Description(S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol is a bifunctional organocatalyst.
(S)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol Preparation Products And Raw materials
Raw materialsTetrahydrofuran-->Ethyl formate-->L-Proline-->PHENYLMAGNESIUM BROMIDE
(S)-(-)-2-[Bis(3,5-dimethylphenyl)hydroxymethyl]pyrrolidine (2S)-(4,4'-DIISOBUTYLPHENYL)PYRROLIDINE METHANOL SULFATE (S)-O-TOLYL-CBS-OXAZABOROLIDINE, 0.5M I& (S)-(-)N-CARBOMETHOXY-ALPHA,ALPHA-DIPHENYL -2-PYRROLIDINEMETHANOL,98% ALPHA,ALPHA-DIPHENYL-L-PROLINOL METHYLBORONIC ACID CYCL-AMIDE ESTER (S,S)-(+)-2,6-BIS[2-(HYDROXYDIPHENYLMETHYL)-1-PYRROLIDINYL-METHYL]-4-METHYLPHENOL (S)-ALPHA,ALPHA-BIS(4-METHOXYPHENYL)-2-PYRROLIDINEMETHANOL (S)-ALPHA,ALPHA-BIS(4-FLUOROPHENYL)-2-PYRROLIDINEMETHANOL (S)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol (S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl}pyrrolidine (S)-2-(Methoxydiphenylmethyl)pyrrolidine (S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]methoxy-methyl}pyrrolidine hydrochloride (S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE 1,1-DIPHENYL-TETRAHYDRO-PYRROLO[1,2-C]OXAZOL-3-ONE (S)-(-)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINYL METHYLTMS ETHER TIMTEC-BB SBB006749 (S)-Tetrahydro-1,3,3-triphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxaborole, 99% (S)-Phenyl oxazaborolidine (S)-(-)-ALPHA,ALPHA-DI(2-NAPHTHYL)-2-PYRROLIDINEMETHANOL

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