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| | Quinic acid Basic information |
| Product Name: | Quinic acid | | Synonyms: | (3R,5R)-1,3,4,5-TETRAHYDROXY-CYCLOHEXANECARBOXYLIC ACID;(-)-QUINIC ACID;QUINIC ACID;(-) QUINIC ACID 500MG NEAT;(-)-QUINIC ACID FOR RESOLUTION OF RACEMATES 98+%;Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1.alpha.,3R,4.alpha.,5R)-;5-beta))-h;5beta)]-alph | | CAS: | 77-95-2 | | MF: | C7H12O6 | | MW: | 192.17 | | EINECS: | 201-072-8 | | Product Categories: | Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;chiral;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Asymmetric Synthesis;Chiral Resolution Reagents;Chiral Resolving Reagents | | Mol File: | 77-95-2.mol |  |
| | Quinic acid Chemical Properties |
| Melting point | 165-170 °C | | alpha | -44 º (c=11.2, H2O) | | Boiling point | 248.13°C (rough estimate) | | density | 1.64 g/cm3 (20℃) | | refractive index | -43.5 ° (C=10, H2O) | | storage temp. | Store below +30°C. | | solubility | 290g/l (experimental) | | pka | 4.27±0.50(Predicted) | | form | Crystalline Powder | | color | White to very slightly yellow | | PH | 2.0 (10g/l, H2O, 20℃) | | optical activity | [α]20/D 43.9°, c = 11.2 in H2O | | Water Solubility | 400 g/l (20 ºC) | | Merck | 14,8059 | | BRN | 2212412 | | InChIKey | AAWZDTNXLSGCEK-WYWMIBKRSA-N | | LogP | -2.023 (est) | | CAS DataBase Reference | 77-95-2(CAS DataBase Reference) | | EPA Substance Registry System | Quinic acid (77-95-2) |
| | Quinic acid Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | D(-)-Quinic Acid is used in the synthesis of anti-influenza/anti-swine flu medication. | | Uses | D-(-)-Quinic acid has been used as a standard to determine the composition of organic acids in bitter gentian teas and in developing cranberry fruit by HPLC. It may be used in the preparation of 3,4-O-isopropylidene-3(R),4(S)-dihydroxycyclohexanone. | | Uses | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. | | Definition | ChEBI: (-)-quinic acid is the (-)-enantiomer of quinic acid. It is a conjugate acid of a (-)-quinate. It is an enantiomer of a (+)-quinic acid. | | General Description | D-(-)-Quinic acid, a plant metabolite, is chiral building block used in multistep chemical synthesis of natural compounds. | | target | Beta Amyloid | alpha-mannosidase | alpha-fucosidase | | Purification Methods | Quinic acid crystallises from H2O with m 174o, and from EtOH with m 168-169o. [McComsey & Maryanoff J Am Chem Soc 59 2652 1994, pK: Timberlake J Chem Soc 2795 1959, Anet & Reynolds Aust J Chem 8 282 1955, Beilstein 10 III 2407, 10 IV 2257.] |
| | Quinic acid Preparation Products And Raw materials |
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