ChemicalBook Product Catalog API Blood System Drugs Haemostatic Drugs Etamsylate

Etamsylate

Etamsylate Basic information
Product Name:Etamsylate
Synonyms:altodor;e141;eselin;md141;2,5-dihydroxy-benzenesulfonicacicompd.withdiethylamine;2,5-dihydroxy-benzenesulfonicacicompd.withn-ethylethanamine(1:1);2,5-dihydroxybenzenesulfonicacidcompd.withn-ethylethanamine;2,5-DihydroxybenzenesulfonicacidcompdwithN-ethylethanamine
CAS:2624-44-4
MF:C10H17NO5S
MW:263.31
EINECS:220-090-7
Product Categories:Other APIs;For the prevention and treatment of bleeding before surgery, but for intestinal bleeding, bleeding and urinary tract bleeding, etc;Amines;Aromatics;Intermediates & Fine Chemicals;API;Pharmaceuticals;Sulfur & Selenium Compounds;2624-44-4
Mol File:2624-44-4.mol
Etamsylate Structure
Etamsylate Chemical Properties
Melting point 125°
density 1.3441 (rough estimate)
refractive index 1.5060 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Very soluble in water, freely soluble in methanol, soluble in anhydrous ethanol, practically insoluble in methylene chloride.
form neat
color White to Pale Red
Merck 14,3722
Stability:Hygroscopic
InChIKeyHBGOLJKPSFNJSD-UHFFFAOYSA-N
CAS DataBase Reference2624-44-4(CAS DataBase Reference)
EPA Substance Registry SystemEthamsylate (2624-44-4)
Safety Information
RTECS DB6145000
HS Code 2921.19.6190
HazardClass IRRITANT
ToxicityLD50 i.v. in mice, rats: 800, 1350 mg/kg (Esteve)
MSDS Information
ProviderLanguage
Etamsylate English
Etamsylate Usage And Synthesis
Chemical PropertiesWhite Solid
UsesHaemostatic / Anti Coagulant
UsesHemostatic.
UsesHemostatic;prostaglandin synthesis inhibitor
DefinitionChEBI: Etamsylate is a sulfonic acid derivative and an organosulfur compound.
Clinical UseShort-term treatment of blood loss in menorrhagiaProphylaxis of surgical bleeding (unlicensed)
MetabolismEtamsylate is excreted unchanged, mainly in the urine.
Etamsylate Preparation Products And Raw materials
Raw materialsDiethylamine-->Sulfur dioxide-->1,4-Benzoquinone-->Diethylaminoethanol
Sulfanilic acid ETAMSYLATE FOR INJECTION Ethyl 2-(Chlorosulfonyl)acetate Amlodipine Besylate Benzenesulfonic acid Folic acid Etamsylate Glycine Diethylamine Calcium dobesilate PHENOLSULFONIC ACID Diethylamine hydrochloride ETAMSYLATE EPE(CRM STANDARD) Ethylamine phosphoric acid Dodecylbenzenesulphonic acid
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