(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol

(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Basic information
Product Name:(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
Synonyms:Crizotinib Impurity 5;100968;benzeneMethanol, 2,6-dichloro-3-fluoro-α-Methyl-, (alphaR)-;BenzeneMethanol,2,6-dichloro-3-fluoro-a-Methyl-, (aR)-;Crizotinib InterMediate;Benzenemethanol, 2,6-dichloro-3-fluoro-α-methyl-, (αR)-;(R)-2,6-Dichloro-3-fluoro-alpha-methylbenzyl Alcohol;(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
CAS:330156-50-8
MF:C8H7Cl2FO
MW:209.04
EINECS:808-063-3
Product Categories:Chiral Compounds
Mol File:330156-50-8.mol
(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Structure
(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Chemical Properties
Melting point 41.0 to 45.0 °C
Boiling point 261 °C
density 1.406
Fp 112 °C
storage temp. 2-8°C
solubility soluble in Methanol
pka13.30±0.20(Predicted)
form powder to crystal
color White to Almost white
InChIKeyJAOYKRSASYNDGH-SCSAIBSYSA-N
Safety Information
HS Code 2906.29.6000
HazardClass IRRITANT
MSDS Information
(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Usage And Synthesis
Description(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is an alcohol derivative and can be used as a pharmaceutical intermediate.
Uses(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is used in the synthesis of anti-tumor molecular targeted drug of Crizotinib (C785000).
(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Preparation Products And Raw materials
Raw materials2,6-Dichloro-3-fluoroacetophenone-->1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHANOL
Preparation Products(1S)-1-(2,6-dichloro-3-fluorophenyl)ethyl acetate-->(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol 2,6-Dichloro-3-fluoroacetophenone 1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHANOL Dichlorofluoroethane Ethanol 2,2,2-TRIFLUOROETHANOL-D3 1-(2,6-DICHLOROPHENYL)ETHANOL Phenethyl alcohol (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Dichloromethylphenylsilane Ethyl acetate Dichlorodiphenylsilane 2-Fluoroethanol

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