Ethylamine hydrochloride

Ethylamine hydrochloride Basic information
Product Name:Ethylamine hydrochloride
Synonyms:monoethylammoniumchloride;ETHYLAMINE HCL;ETHYLAMINE HYDROCHLORIDE;ETHYLAMMONIUM CHLORIDE;ETHANAMINE HYDROCHLORIDE;MONOETHYLAMINE HCL;AMINOETHANE HYDROCHLORIDE;MONOETHYLAMINE HYDROCHLORIDE
CAS:557-66-4
MF:C2H8ClN
MW:81.54
EINECS:209-182-8
Product Categories:Amine Salts;Nitrogen Compounds;Organic Building Blocks;Chemical Synthesis;Organic Bases;Synthetic Reagents;Pharmaceutical Intermediates
Mol File:557-66-4.mol
Ethylamine hydrochloride Structure
Ethylamine hydrochloride Chemical Properties
Melting point 107-108 °C(lit.)
Boiling point 95.79°C (rough estimate)
density 1,22 g/cm3
refractive index 1.4202 (estimate)
storage temp. Store below +30°C.
solubility soluble
form Solid
color White to Off-White
Water Solubility soluble
Sensitive Hygroscopic
Merck 14,3762
BRN 3589312
Stability:Hygroscopic
CAS DataBase Reference557-66-4(CAS DataBase Reference)
EPA Substance Registry SystemEthylamine hydrochloride (557-66-4)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 1
RTECS KH2495000
3-10-23
TSCA Yes
HS Code 29211980
ToxicityLD50 orally in Rabbit: > 3200 mg/kg
MSDS Information
ProviderLanguage
Ethylammonium chloride English
ACROS English
SigmaAldrich English
ALFA English
Ethylamine hydrochloride Usage And Synthesis
Chemical Propertieswhite to off-white crystals
UsesEthylamine Hydrochloride a chemical used in various chemical organic syntheses and biological studies. It is used in production of resins and rubber latex; also used in oil refining and organic syntheses.
ApplicationEthylaminehydrochloride is used as a raw material for organic synthesis. Its free base ethylamine is used in the diethyldiazene, dimethylolethyltriazone, ethylcyanopyrolidone disperse and 1,3-diethylthiourea. It is a precursor used for the preparation of benzilnitrate, detergents, rayon, rocket propellant and alkyl isocyanates, which finds application in the manufacture of pharmaceuticals.
PreparationEthylamine can be synthesized by ethanol and ammonia are combined in the presence of an oxide catalyst:
CH3CH2OH + NH3 → CH3CH2NH2 + H2O
Ethylamine could then be solvent extracted or boiled out of hoffman turned to Hydrochloride with HCl and then freebased with caustic to be distilled pure.
of course an excess of caustic when freebasing would be a good idea as it would hold onto most of the water created from the basing of a hydrochloride with caustic.
Purification MethodsCrystallise the hydrochloride from absolute EtOH or MeOH/CHCl3, wash with dry ether and dry it in a vacuum. [Beilstein 4 IV 310.]
PrecautionsHygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
Ethylamine Pyridine hydrochloride Triethylamine hydrochloride Ethambutol dihydrochloride DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Topotecan hydrochloride Calcium chloride Sodium chloride Triethylamine Ferric chloride Choline chloride N-(4-CHLORO-PHENYL)-OXALAMIC ACID ETHYL ESTER Sulfuryl chloride Ammonium chloride Polyvinyl chloride COBALT ETHYLENE DIAMINE CHLORIDE Potassium chloride Cysteamine hydrochloride

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