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3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide

3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide Basic information
Product Name:3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide
Synonyms:Didesmethyl Sumatriptan;1H-Indole-5-methanesulfonamide, 3-(2-aminoethyl)-N-methyl-;3-(2-AMINOETHYL)-N-METHYLINDOL-5-YLMETHANESULFONAMIDE;3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide Didesmethyl Sumatriptan;[3-(2-aMinoethyl)-1-Methyl-1H-indol-5-yl]MethanesulfonaMide;[3-(2-Aminoethyl)-1H-indol-5-yl]-N-methylmethanesulphonamide;1-(3-(2-AMinoethyl)-1H-indol-5-yl)-N-MethylMethanesulfonaMide;SuMatriptan EP IMpurity E
CAS:88919-22-6
MF:C12H17N3O2S
MW:267.35
EINECS:
Product Categories:Chemical Amines;Amines;Indole Derivatives;Sulfur & Selenium Compounds
Mol File:88919-22-6.mol
3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide Structure
3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide Chemical Properties
Melting point 151-154°C
Boiling point 514.5±60.0 °C(Predicted)
density 1.329±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Acetonitrile (Slightly, Heated), Methanol (Slightly)
form Solid
pka11.30±0.40(Predicted)
color Light Yellow to Brown
Safety Information
MSDS Information
3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide Usage And Synthesis
Chemical PropertiesOff-White Solid
Uses3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide (Didesmethyl Sumatriptan) (Sumatriptan EP Impurity E) is an antimigraine agent. A Sumatriptan intermediate.
3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide Preparation Products And Raw materials
CYCLAZOSIN HYDROCHLORIDE Sumatriptan succinate Tazobactam Impurity B SuMatriptan DiMer IMpurity Discontinued Zolmitriptan [3-[2-(diMethylaMino)ethyl]-2-[[3-[2-(diMethylaMino)ethyl]-1H-indol-5-yl]Methyl]-1H-indol-5-yl]-N-MethylMethanesulfonaMide, succinate salt N,N-DIMETHYL-2-(5-METHYLSULFAMOYLMETHYL-1H-INDOL-3-YL)-2-OXO-ACETAMIDE Sumatriptan-d6 N,N-DIMETHYL-2-[5-(PYRROLIDINE-1-SULFONYLMETHYL)-1H-INDOL-3-YL]-ACETAMIDE ALMOTRIPTAN 2-[5-(PYRROLIDINE-1-SULFONYLMETHYL)-1H-INDOL-3-YL]-ETHYLAMINE N,N-DIMETHYL-2-(5-METHYLSULFAMOYLMETHYL-1H-INDOL-3-YL)-ACETAMIDE 3-(2-DIMETHYLAMINO-ETHYL)-5-(PYRROLIDINE-1-SULFONYLMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID Sumatriptan SUMATRIPTAN-D6 SUCCINATE 3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide Almotriptan [3H]SUMATRIPTAN
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