2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid

2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid Basic information
Product Name:2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid
Synonyms:N-[2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]TAURINE;N-TRIS(HYDROXYMETHYL)METHYL-2-AMINO-ETHANESULPHONIC ACID;N-TRIS(HYDROXYMETHYL)METHYL-2-AMINOETHANESULFONIC ACID;2-[TRIS(HYDROXYMETHYL)METHYL]-2-AMINOETHANE SULFONIC ACID;2-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-ETHANESULFONIC ACID;2-[[TRIS(HYDROXYMETHYL)METHYL]AMINO]ETHANESULFONIC ACID;2-([2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]AMINO)ETHANESULFONIC ACID;TES free acid
CAS:7365-44-8
MF:C6H15NO6S
MW:229.25
EINECS:230-906-3
Product Categories:Biochemistry;Good's Buffers;Buffer
Mol File:7365-44-8.mol
2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid Structure
2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid Chemical Properties
Melting point ~225 °C (dec.)
density 1.260 (estimate)
refractive index 1.5500 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility H2O: 1 M at 20 °C, clear, colorless
form Crystalline Powder
color White
OdorOdorless
PH3.5-5.0 (25℃, 1M in H2O)
PH Range6.8 - 8.2
pka7.5(at 25℃)
Water Solubility SOLUBLE
λmaxλ: 260 nm Amax: 0.055
λ: 280 nm Amax: 0.045
Merck 14,9176
BRN 1957061
InChIKeyJOCBASBOOFNAJA-UHFFFAOYSA-N
CAS DataBase Reference7365-44-8(CAS DataBase Reference)
EPA Substance Registry SystemEthanesulfonic acid, 2-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (7365-44-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 1
TSCA Yes
HS Code 29221980
MSDS Information
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2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid English
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SigmaAldrich English
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2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid Usage And Synthesis
Chemical PropertiesWhite/clear crystalline powder
UsesA structural analog to Tris buffer.
UsesBiological buffer.
UsesTES is a commonly used buffering agent.
DefinitionChEBI: N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid is a Good's buffer substance, pKa = 7.5 at 20 ℃. It is a member of ethanolamines, an amino sulfonic acid and a TES. It is functionally related to a taurine. It is a tautomer of a N-tris(hydroxymethyl)methyl-2-ammonioethanesulfonate.
Purification MethodsCrystallise the acid from hot EtOH containing a little water.
2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid Preparation Products And Raw materials
Raw materialsSodium ethylenesulphonate-->Tris(hydroxymethyl)aminomethane-->1-Bromo-2-chloroethane
N-(Tris(hydroxymethyl)methyl)-2-aminoethanesulfonic acid sodium salt Phosphate buffer containing Tween 20 (PBS-T tablets) Diammonium 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate) PBS Tablets 3-[N,N-Bis(hydroxyethyl)amino]-2-hydroxypropanesulphonic acid sodium salt TAPS TRIS hydrochloride CHAPS Sodium Citrate buffer(0.1mol/L, pH4.5, sterile) Tris-MOPS Buffer,10× N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid sodium salt 3-[N,N-Bis(2-hydroxyethyl)amino]-2-hydroxy-1-propanesulfonic acid 3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid sodium salt TAPSO 2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid N-TRIS(HYDROXYMETHYL)METHYL-2-AMINOETHANESULFONIC ACID-D15 2-([2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]AMINO)ETHANESULFONIC ACID HEMISODIUM SALT Tris(hydroxymethyl)aminomethane

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