2,4-DIFLUOROBENZENESULFONYL CHLORIDE

2,4-DIFLUOROBENZENESULFONYL CHLORIDE Basic information
Product Name:2,4-DIFLUOROBENZENESULFONYL CHLORIDE
Synonyms:TIMTEC-BB SBB003423;2,4-DIFLUOROBENZENE-1-SULFONYL CHLORIDE;2,4-DIFLUOROBENZENESULFONYL CHLORIDE;2,4-DIFLUOROBENZENESULPHONYL CHLORIDE;AKOS B019394;ART-CHEM-BB B019394;BUTTPARK 23\07-79;2,4-Difluorobenzenesulfonyl chloride,98%
CAS:13918-92-8
MF:C6H3ClF2O2S
MW:212.6
EINECS:629-141-1
Product Categories:Fluorine series;Aromatic Halides (substituted);Benzenesulfonyl chloride;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
Mol File:13918-92-8.mol
2,4-DIFLUOROBENZENESULFONYL CHLORIDE Structure
2,4-DIFLUOROBENZENESULFONYL CHLORIDE Chemical Properties
Boiling point 101-102 °C (1 mmHg)
density 1.581 g/mL at 25 °C(lit.)
refractive index 1.5187
Fp >110°C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form Liquid
color Clear colorless to light yellow
Sensitive Moisture Sensitive
BRN 2970373
InChIKeyFJSAJUXIHJIAMD-UHFFFAOYSA-N
CAS DataBase Reference13918-92-8(CAS DataBase Reference)
Safety Information
Hazard Codes C,Xi
Risk Statements 34
Safety Statements 45-36/37/39-26
RIDADR 3265
WGK Germany 3
Hazard Note Corrosive
HazardClass 8
PackingGroup II
HS Code 29049090
MSDS Information
ProviderLanguage
ACROS English
ALFA English
2,4-DIFLUOROBENZENESULFONYL CHLORIDE Usage And Synthesis
Chemical Propertiesclear colorless to light yellow liquid
Uses2,4-Difluorobenzenesulfonyl chloride may be used in the preparation of 2,4-difluoro-N,N-dimethylbenzenesulfonamide, a precursor for poly(aryl ether sulfonamide)s.
It may be used in the preparation of the following benzenesulfonamide quinoline derivatives with potent anti-HIV-1 (human immunodeficiency virus type 1) activity:
  • 2,4-difluoro-N-methyl-N-(quinolin-8-yl)benzenesulfonamide
  • N-ethyl-2,4-difluoro-N-(quinolin-8-yl)benzenesulfonamide
  • 2,4-difluoro-N-(quinolin-8-yl)benzenesulfonamide
General Description2,4-Difluorobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative.
2,4-DIFLUOROBENZENESULFONYL CHLORIDE Preparation Products And Raw materials
Preparation Products2,4-difluoro-N-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)benzenesulfonamide-->2',4'-Difluoroacetophenone-->N-(5-bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide-->N-(5-broMo-2-chloropyridin-3-yl)-2,4-difluorobenzenesulfonaMide
2,6-DIFLUOROBENZENESULFONYL CHLORIDE, 97,2,6-DIFLUOROBENZENESULFONYL CHLORIDE BUTTPARK 144\07-12 2,3-dibromo-5,6-difluorobenzenesulfonyl chloride 5-BROMO-2,4-DIFLUOROBENZENESULFONYL CHLORIDE 3-CHLOROSULFONYL-2,6-DIFLUORO-BENZOIC ACID 4-[(aminosulfonyl)amino]-3,5-difluorobenzenesulfonyl chloride 5-(chlorosulfonyl)-2,4-difluorobenzoic acid 5-CHLORO-2,4-DIFLUOROBENZENESULFONYL CHLORIDE 2,4-DIFLUORO-5-NITROBENZENESULFONYL CHLORIDE 2,4-DIFLUOROBENZENESULFONYL CHLORIDE BUTTPARK 80\07-45 2,3,4-TRIFLUOROBENZENESULFONYL CHLORIDE 2-BROMO-4,6-DIFLUOROBENZENESULFONYL CHLORIDE 2,5-DIBROMO-3,6-DIFLUOROBENZENESULFONYL CHLORIDE PENTAFLUOROBENZENESULFONYL CHLORIDE 2,4,6-TRIFLUOROBENZENESULFONYL CHLORIDE 2,4,5-Trifluorobenzenesulfonyl chloride BUTTPARK 80\07-37

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