1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1h-1,2,4-triazole

1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1h-1,2,4-triazole Basic information
Product Name:1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1h-1,2,4-triazole
Synonyms:1-[2-(2,4-Difluorophenyl)-oxiranyl]-methyl-1H-1,2,4-triazole;2-(2,4-Difluorophenyl)-2,3-epoxy-1-(1H-1,2,4-triazol-1-yl)propane;2-(2,4-Difluorophenyl)-2-[(1H-1,2,4-triazol-1-yl)Methyl]oxirane;Fluconazole Epoxy IMpurity;l-[2-(2,4-Difluoro Phenyl)Oxiranyl] Methyl-lH-1,2,4-Triazole;Fluconazole EP Impurity G;Fluconazole Impurity L;1 (-2-(2,4- DIFLUOROPHNEYL)-2,3- EPOXY PROPYL)-1H-1,2,4- TRIAZOLE METHANE SULFONATE
CAS:86386-76-7
MF:C11H9F2N3O
MW:237.21
EINECS:
Product Categories:Aromatics;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:86386-76-7.mol
1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1h-1,2,4-triazole Structure
1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1h-1,2,4-triazole Chemical Properties
Melting point 70-73°C
Boiling point 370.5±52.0 °C(Predicted)
density 1.46±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Hexanes (Sligh
form Solid
pka2.75±0.10(Predicted)
color Pale Yellow to Light Yellow
Safety Information
MSDS Information
1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1h-1,2,4-triazole Usage And Synthesis
Chemical PropertiesWhite Solid
Uses1-[2-(2,4-Difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole (Fluconazole EP Impurity G) is an epoxy impurity of the antifungal agent Fluconazole (F421000).
Uses1-[2-(2,4-Difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole is an epoxy impurity of the antifungal agent Fluconazole (F421000).
1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1h-1,2,4-triazole Preparation Products And Raw materials
FLUCONAZOLE RELATED COMPOUND B (10 MG) (2-(4-FLUOROPHENYL)-1,3-BIS(1 H-1,2,4-TRIAZOL-1 -YL)-PROPAN-2-OL) Fluconazole IMpurity I FLUCONAZOLE IMPURITY C 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone 2-(2,4-Difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)-1,2-propanediol (2RS)-1-bromo-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol 2-(4-FLUOROPHENYL)OXIRANE 1H-1,2,4-Triazole-1-propanol(9CI) 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL 1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-1h-1,2,4-triazole 1-[(2R,3S)-2-(2,4-DIFLUORO-PHENYL)-3-METHYL-OXIRANYLMETHYL]-1H-[1,2,4]TRIAZOLE 2-amino-1-(2,4-difluorophenyl)ethanol 1-[2-(2,4-Difluorophenyl)-2,3-Epoxypropyl]-1H-1,2,4-Triazole Methanesulfonate

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