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| | 5-Nonanone Basic information |
| Product Name: | 5-Nonanone | | Synonyms: | DIBUTYL KETONE;DI-N-BUTYL KETONE;(n-C4H9)2CO;5-Nonanon;5-Oxononane;Butyl ketone;butylketone;Dibutylketon | | CAS: | 502-56-7 | | MF: | C9H18O | | MW: | 142.24 | | EINECS: | 207-946-5 | | Product Categories: | | | Mol File: | 502-56-7.mol |  |
| | 5-Nonanone Chemical Properties |
| Melting point | -50 °C (lit.) | | Boiling point | 186-187 °C (lit.) | | density | 0.826 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.419(lit.) | | Fp | 141 °F | | storage temp. | Sealed in dry,Room Temperature | | form | Liquid | | color | Clear colorless to slightly yellow | | Odor | Data not available. | | Water Solubility | 256mg/L(25 ºC) | | BRN | 1743583 | | CAS DataBase Reference | 502-56-7(CAS DataBase Reference) | | NIST Chemistry Reference | 5-Nonanone(502-56-7) | | EPA Substance Registry System | 5-Nonanone (502-56-7) |
| Safety Statements | 23-24/25 | | RIDADR | UN 1224 3/PG 3 | | WGK Germany | 3 | | RTECS | RA8230000 | | TSCA | Yes | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29141990 | | Hazardous Substances Data | 502-56-7(Hazardous Substances Data) | | Toxicity | mouse,LD50,intravenous,138mg/kg (138mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX),Acta Pharmacologica et Toxicologica. Vol. 37, Pg. 56, 1975. |
| | 5-Nonanone Usage And Synthesis |
| Chemical Properties | CLEAR COLOURLESS TO SLIGHTLY YELLOW LIQUID | | Chemical Properties | 5-Nonanone is a stable and colorless-to-light yellow
liquid.
No human odor threshold was identified for 5-nonanone.
However, Laska et al. demonstrated using a conditioning
paradigm that the olfactory threshold of squirrel monkeys
and pigtail caques for 5-nonanone is below 1 ppb . | | Uses | 5-Nonanone is used in preparation of 6-(1,2,4-oxadiazol-5-yl)chroman-4-one derivatives as S1P1 receptor modulators and methods for preparing them. | | Synthesis Reference(s) | Journal of the American Chemical Society, 89, p. 2738, 1967 DOI: 10.1021/ja00987a043
The Journal of Organic Chemistry, 52, p. 5570, 1987 DOI: 10.1021/jo00234a012
Tetrahedron Letters, 7, p. 6145, 1966 | | General Description | Colorless to light yellow liquid. Floats on water. Freezing point is 21°F. | | Air & Water Reactions | Highly flammable. | | Reactivity Profile | Ketones, such as 5-Nonanone, are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4. May attack some forms of plastics [USCG, 1999]. | | Health Hazard | Inhalation causes irritation of nose and throat. Ingestion causes irritation of mouth and stomach. Contact with eyes or skin causes irritation. | | Chemical Reactivity | Reactivity with Water No reaction; Reactivity with Common Materials: May attack some forms of plastics; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent. | | Biochem/physiol Actions | 5-Nonanone induces clinical neuropathy in rats. |
| | 5-Nonanone Preparation Products And Raw materials |
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