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| | 12-AMINODODECANOIC ACID Basic information |
| | 12-AMINODODECANOIC ACID Chemical Properties |
| Melting point | 185-187 °C (lit.) | | Boiling point | 349.7±15.0 °C(Predicted) | | density | 0.957±0.06 g/cm3(Predicted) | | vapor pressure | 0Pa at 25℃ | | Fp | 280 °C | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Aqueous Acid (Slightly), Aqueous Base (Slightly) | | form | Solid | | pka | pK1: 4.648(+1) (25°C) | | color | White to Off-White | | Water Solubility | 137mg/L at 20℃ | | BRN | 907502 | | LogP | -0.607 at 24.6℃ | | CAS DataBase Reference | 693-57-2(CAS DataBase Reference) | | EPA Substance Registry System | 12-Aminolauric acid (693-57-2) |
| | 12-AMINODODECANOIC ACID Usage And Synthesis |
| Description | 12-Aminododecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond. | | Chemical Properties | Light beige powder | | Uses | 12-Aminolauric Acid is an amino acid used as a reagent in organic synthesis of several compounds including phenylbutazone which is a new long-acting agent which displays improved pharmacokinectics based on human serum albumin as a drug carrier. | | Definition | ChEBI: 12-aminododecanoic acid is an omega-amino fatty acid that is dodecanoic acid in which one of the terminal amino hydrogens has been replaced by an amino group. It has a role as a bacterial metabolite. It is an omega-amino fatty acid and a medium-chain fatty acid. | | Flammability and Explosibility | Nonflammable |
| | 12-AMINODODECANOIC ACID Preparation Products And Raw materials |
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