2-Acetoxy-2-methylpropionyl bromide Usage And Synthesis
Chemical Properties
light yellow clear liquid
Uses
1-Bromocarbonyl-1-methylethyl acetate (α-Acetoxyisobutyryl bromide) may be used:
in the chemoenzymatic synthesis of (1R,2S)-1,2-epoxy-1,2-dihydroacridine (acridine 1,2-oxide)
in the synthesis of protected 3′-deoxyadenosine and 3′-deoxyguanosine
as reagent for deoxygenation of vicinal diols, as well as in the preparation of 2′,3′-dideoxycytidine and other dideoxy and deoxynucleosides from the corresponding ribo series.
General Description
1-Bromocarbonyl-1-methylethyl acetate (α-Acetoxyisobutyryl bromide) participates in the conversion ofadenosine to trans-3′(2′)-bromo-2′(3′)-acetates, via glycosyl cleavage.
2-Acetoxy-2-methylpropionyl bromide Preparation Products And Raw materials
