8-Quinolinecarboxylic acid

8-Quinolinecarboxylic acid Basic information
Product Name:8-Quinolinecarboxylic acid
Synonyms:RARECHEM AL BE 0482;QUINOLINE-8-CARBOXYLIC ACID;8-QUINOLINECARBOXYLIC ACID;AKOS BBS-00005343;QUINOLINE-8-CARBOXYLIC ACID, 98+%;8-Quinolinecarboxylic;8-quinlinecarboxylic acid;8-Carboxyquinoline
CAS:86-59-9
MF:C10H7NO2
MW:173.17
EINECS:632-930-3
Product Categories:Building Blocks;Heterocyclic Building Blocks;Quinolines, Quinazolines and derivatives;Quinolines;Quinolinecarboxylic Acids, etc.;quinoline;Quinoline Derivertives
Mol File:86-59-9.mol
8-Quinolinecarboxylic acid Structure
8-Quinolinecarboxylic acid Chemical Properties
Melting point 183-185 °C (lit.)
Boiling point 303.81°C (rough estimate)
density 1.2427 (rough estimate)
refractive index 1.5200 (estimate)
storage temp. Sealed in dry,Room Temperature
pka1.82(at 25℃)
form Crystalline Powder
color Light brown
Water Solubility Insoluble
Merck 14,8070
BRN 19176
InChIKeyQRDZFPUVLYEQTA-UHFFFAOYSA-N
CAS DataBase Reference86-59-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
HazardClass IRRITANT
HS Code 29334900
MSDS Information
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8-Quinolinecarboxylic acid English
ACROS English
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8-Quinolinecarboxylic acid Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses8-Quinolinecarboxylic acid may be used in the synthesis of novel oxorhenium(V) complexes incorporating quinoline and isoquinoline carboxylic acid derivatives, chiral 1,2,3,4-tetrahydroquinolinyl-oxazoline compounds, used as ligands for Ru-catalyzed asymmetric transfer hydrogenation of ketones and chiral quinolinyl-oxazoline compounds, used as ligands for Cu(II) catalyzed asymmetric cyclopropanation.
Uses8-Quinolinecarboxylic acid may be used in the synthesis of:
  • novel oxorhenium(V) complexes incorporating quinoline and isoquinoline carboxylic acid derivatives
  • chiral 1,2,3,4-tetrahydroquinolinyl-oxazoline compounds, used as ligands for Ru-catalyzed asymmetric transfer hydrogenation of ketones
  • chiral quinolinyl-oxazoline compounds, used as ligands for Cu(II) catalyzed asymmetric cyclopropanation
General DescriptionHerbicide 8-quinolinecarboxylic acid and its removal from aqueous solution using sodium montmorillonite, acidic montmorillonite and organo-acidic montmorillonite has been reported.
Purification MethodsCrystallise the acid from water, aqueous EtOH, EtOH or *C6H6. The ethyl ester has m 45o and b 194-197o/13mm. [Beilstein 22 H 81, 22 III/IV 1200, 22/3 V 217.]
8-Quinolinecarboxylic acid Preparation Products And Raw materials
Raw materialsEthanol-->Ethyl acetate-->Sulfuric acid-->Glycerol-->Anthranilic acid-->Sodium iodide-->Sodium iodide dihydrate
Preparation ProductsNorfloxacin-->quinoline-8-carbonyl chloride-->METHYLQUINOLINE-8-CARBOXYLATE
QUINOLINE-4-CARBOXYLIC ACID Ethyl 2-(Chlorosulfonyl)acetate 6-Nitroquinoline-8-carboxylic acid AURORA 19849 6-chloroquinoline-8-carboxylic acid AURORA 19879 8-Quinolinecarboxylic acid Acridine-4,9-dicarboxylic acid monohydrate 4-Acridinecarboxylic acid, 9-((3-(dimethylamino)propyl)amino)-1-nitro- , methyl ester Ethoxyquin RARECHEM AL BI 0482 2-Ethyl-3-methylquinoline-8-carboxylicacid 6-bromoquinoline-8-carboxylic acid Quinolinic acid AURORA 19878 AURORA 19866 AURORA 19865 QUINMERAC

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