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| | 7-Methoxyflavone Basic information |
| | 7-Methoxyflavone Chemical Properties |
| Melting point | 110-112 °C(lit.) | | Boiling point | 421.2±45.0 °C(Predicted) | | density | 1.240±0.06 g/cm3 (20 ºC 760 Torr) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMF: 30 mg/ml,DMSO: 15 mg/ml,Ethanol: 5 mg/ml | | form | powder to crystal | | color | White to Light yellow | | LogP | 3.470 (est) | | CAS DataBase Reference | 22395-22-8(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29145019 |
| | 7-Methoxyflavone Usage And Synthesis |
| Description | 7-Methoxyflavone is a natural compound and non-steroidal because it binds reversibly with aromatase which is an enzyme that helps produce estrogen through the conversion of androgen (testosterone) to estrogen. It has strong aromatase inhibiting properties, superior bioavailability, and strong resistance to hepatic metabolism/breakdown. | | Definition | ChEBI: 7-Methoxyflavone is a member of flavonoids and an ether. | | benefits | 7-methoxyflavone is popular nowadays as one of the most powerful aromatase inhibitor and testosterone booster. It is isolated from Zornia brasiliensis. It might change how the body breaks down chemicals called hormones. Some people think this might cause the body to have more of the hormone called testosterone. Testosterone can help build muscle, but can also cause serious side effects. | | Biological Activity | 7-Methoxyflavone is a flavone that has been found in Z. brasiliensis and has diverse biological activities. It inhibits aromatase (IC50 = 1.9 μM in a cell-free assay) and LPS-induced nitric oxide (NO) production by 17.74% in RAW 264.7 macrophages when used at a concentration of 20 μM. 7-Methoxyflavone activates androgen and/or glucocorticoid receptor transcriptional activity in a reporter assay and has antinociceptive effects in the acetic acid-induced writhing test in mice (ED50 = 82.5 μmol/kg). |
| | 7-Methoxyflavone Preparation Products And Raw materials |
| Raw materials | (2Z)-2-benzylidene-6-methoxy-1-benzofuran-3(2H)-one-->1-(2-hydroxy-4-methoxyphenyl)-3-phenylpropane-1,3-dione-->2'-hydroxy-4' methoxydihydrochalcone-->4H-1-Benzopyran-4-one, 3-benzoyl-7-methoxy-2-phenyl--->1-(2,4-dimethoxyphenyl)-3-phenylpropane-1,3-dione-->2-HYDROXY-1-(4-METHOXYPHENYL)-1-ETHANONE-->7-METHOXYFLAVANONE-->Paeonol-->4H-1-BENZOPYRAN-4-ONE, 2,3-DIHYDRO-7-METHOXY--->7-METHOXYISOFLAVONE-->2-Iodo-5-Methoxyphenol-->(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZENE-->Benzaldehyde-->Phenylacetylene |
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Robinin
3,5,3',4'-TETRAHYDROXY-7-METHOXYFLAVONE,3,3,4,5-TETRAHYDROXY-7-METHOXYFLAVONE,3,3',4',5'-TETRAHYDROXY-7-METHOXYFLAVONE,3,3',4',5-TETRAHYDROXY-7-METHOXYFLAVONE
3,7,3',4'-TETRAMETHYLGOSSYPETIN
5,7-DIMETHOXYFLAVONE
5-HYDROXY-7-METHOXYFLAVONE
7,3'-DIMETHOXYFLAVONE
3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE
Tangeretin
3'-BENZYLOXY-4',5,6,7-TETRAMETHOXYFLAVONE
3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE
TAMARIXETIN-7-O-RUTINOSIDE
APIIN
3',5'-Dimethoxytricetin 7-O-β-D-glucopypranoside
4',7-DIMETHOXY-3,3',5-TRIHYDROXYFLAVONE
SINENSETIN
QUERCETIN-3,7,3',4'-TETRAMETHYL ETHER
RHOIFOLIN
EUPATORIN-5-METHYL ETHER
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