3-AMINO-ISONICOTINIC ACID ETHYL ESTER

3-AMINO-ISONICOTINIC ACID ETHYL ESTER Basic information

Product Name:	3-AMINO-ISONICOTINIC ACID ETHYL ESTER
Synonyms:	Ethyl3-amino-4-pyridinecarboxylate;3-Amino-isonicotinic acid ethyl ester ,98%;Isonicotinic acid, 3-amino-, ethyl ester (8CI);Ethyl 3-aminopyridine-4-carboxylate, 4-(Ethoxycarbonyl)pyridin-3-amine;ethyl 3-aMinopyridin-4-carboxylate;ETHYL 3-AMINOPYRIDINE-4-CARBOXYLATE;3-AMINOPYRIDINE-4-CARBOXYLIC ACID ETHYL ESTER;3-AMINO-ISONICOTINIC ACID ETHYL ESTER
CAS:	14208-83-4
MF:	C8H10N2O2
MW:	166.18
EINECS:
Product Categories:	Heterocycle-Pyridine series;Pyridine;pharmacetical;Esters;Pyridines;API intermediates;Pyrazoles
Mol File:	14208-83-4.mol

3-AMINO-ISONICOTINIC ACID ETHYL ESTER Chemical Properties

Melting point	170-175
Boiling point	304.0±22.0 °C(Predicted)
density	1.192±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
pka	4.13±0.18(Predicted)
color	Light orange to Yellow to Green
CAS DataBase Reference	14208-83-4(CAS DataBase Reference)

Safety Information

MSDS Information

3-AMINO-ISONICOTINIC ACID ETHYL ESTER Usage And Synthesis

Chemical Properties	Off-white powder or chunks solid
Uses	3-Amino-isonicotinic Acid Ethyl Ester acts as a reagent for the synthetic preparation of heteroaryl compounds as PDE-10 inhibitors useful in treatment and prevention of CNS, metabolic and other diseases. Also in the design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.

3-AMINO-ISONICOTINIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials	Ethanol-->Sodium hydroxide-->Methanol-->Acetic acid-->Thionyl chloride-->Sodium carbonate-->Chloroform-->Government regulation-->Magnesium sulfate-->Acetic anhydride-->Acetamide-->tert-Butyl methyl ether-->3,4-Pyridinedicarboxylic acid
Preparation Products	Ethyl 5-amino-2-chloropyridine-4-carboxylate

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