PHENYL-P-BENZOQUINONE

PHENYL-P-BENZOQUINONE Basic information
Product Name:PHENYL-P-BENZOQUINONE
Synonyms:2-Phenyl-[1,4]benzoquinone;2-Phenyl-1,4-benzoquinone;2-phenyl-2,5-cyclohexadiene-1,4-dione;2-Phenylbenzoquinone;2-phenyl-p-benzoquinon;4-dione,2-phenyl-5-cyclohexadiene-1;o-phenylbenzoquinone;p-Benzoquinone, 2-phenyl-
CAS:363-03-1
MF:C12H8O2
MW:184.19
EINECS:206-654-5
Product Categories:
Mol File:363-03-1.mol
PHENYL-P-BENZOQUINONE Structure
PHENYL-P-BENZOQUINONE Chemical Properties
Melting point 111-115 °C
Boiling point 278.14°C (rough estimate)
density 1.1336 (rough estimate)
refractive index 1.6086 (estimate)
storage temp. 2-8°C
form Chunks and Powder
color Yellow-brown
EPA Substance Registry System2,5-Cyclohexadiene-1,4-dione, 2-phenyl- (363-03-1)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-42/43-20/21/22
Safety Statements 37/39-26-36
RTECS DK6650000
HS Code 29146990
Toxicitydnd-rat-par 50 mg/L JJCREP78,1027,87
MSDS Information
ProviderLanguage
ACROS English
PHENYL-P-BENZOQUINONE Usage And Synthesis
Chemical PropertiesYellow-brown chunks and powder
UsesPhenylquinone is used for small molecule-based targeting of TTD-A dimerization to control TFIIH transcriptional activity whichrepresents a potential strategy for anticancer therapy.
Synthesis Reference(s)Journal of the American Chemical Society, 118, p. 2509, 1996 DOI: 10.1021/ja954009q
Safety ProfilePoison by intraperitoneal route. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes
Purification MethodsCrystallise the quinone from heptane, pet ether (b 60-70o), *C6H6 (m 113.5-114.5o) or EtOH (m 112-113o) and sublime it in vacuo. [Carlson & Miller J Am Chem Soc 107 479 1985, Beilstein 7 H 740, 7 III 3764.]
PHENYL-P-BENZOQUINONE Preparation Products And Raw materials
RARECHEM BW GA 0135 2-(4-ETHOXYPHENYL)-P-BENZOQUINONE RARECHEM BW GA 0131 2-(4-METHOXYPHENYL)-P-BENZOQUINONE 2,5-DIHYDROXY-3-(1-METHYL-1H-INDOL-2-YL)-6-PHENYL-[1,4]BENZOQUINONE 2,5-DIHYDROXY-3-(4-METHOXYPHENYL)-6-PHENYL-1,4-BENZOQUINONE RARECHEM BW GA 0132 2-(4-TOTYL)-P-BENZOQUINONE RARECHEM BW GA 0126 PHENYL-P-BENZOQUINONE 2,5-DIHYDROXY-3-(1-METHYLINDOL-3-YL)-6-PHENYL-1,4-BENZOQUINONE 2,5-DIPHENYL-P-BENZOQUINONE 2-(4-NITROPHENYL)BENZO-1,4-QUINONE N,N,N,N-TETRAKIS(4-DIBUTYLAMINOPHENYL)-P-BENZOQUINONE RARECHEM BW GA 0134 2-(4-HYDROXYCARBONYLPHENYL)-P-BENZOQUINONE 1,4-Benzoquinone RARECHEM BW GA 0133

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