|
| | Tetraethyl orthocarbonate Basic information |
| | Tetraethyl orthocarbonate Chemical Properties |
| Melting point | 222 °C | | Boiling point | 159 °C (lit.) | | density | 0.919 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.392(lit.) | | Fp | 127 °F | | storage temp. | Inert atmosphere,Room Temperature | | solubility | soluble in Chloroform, Methanol | | form | clear liquid | | color | Colorless to Almost colorless | | Specific Gravity | 0.919 | | Water Solubility | Insoluble | | Sensitive | Moisture Sensitive | | BRN | 1747401 | | CAS DataBase Reference | 78-09-1(CAS DataBase Reference) | | NIST Chemistry Reference | Ethane, 1,1',1'',1'''-[methanetetrayltetrakis(oxy)]tetrakis-(78-09-1) | | EPA Substance Registry System | Ethane, 1,1',1'',1'''-[methanetetrayltetrakis(oxy)]tetrakis- (78-09-1) |
| | Tetraethyl orthocarbonate Usage And Synthesis |
| Chemical Properties | clear colorless liquid | | Uses | Tetraethyl Orthocarbonate is used in the synthesis of chemokine receptor-5 inhibitors against HIV-1, benzobisoxazoles and in the preparation of organic semiconductors. It is also employed in the synthesis of 2,7-dimethylene-1,4,6,9-tetraoxaspiro[4,4]nonane and in the synthesis of cross linked poly(orthocarbonate)s used as organic solvent absorbent. | | Purification Methods | Likely impurities are hydrolysis products. Shake the orthocarbonate with brine (saturated NaCl, dilute with a little Et2O if amount of material is small) and dry (MgSO4). The organic layer is filtered off and evaporated, and the residue is distilled through a helices packed fractionating column with a total reflux partial take-off head. All distillations can be done at atmospheric pressure in an inert atmosphere (e.g. N2). [Roberts & McMahon Org Synth Coll Vol IV 457 1963, Connolly & Dyson J Chem Soc 828 1937, Tieckelmann & Post J Org Chem 13 266 1948, for review see Kantlehner et al. Justus Liebigs Ann Chem 507 207 1982, Beilstein 3 IV 6.] |
| | Tetraethyl orthocarbonate Preparation Products And Raw materials |
|
