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| | Biphenyl dimethyl dicarboxylate Basic information |
| | Biphenyl dimethyl dicarboxylate Chemical Properties |
| Melting point | 213-215 °C (lit.) | | Boiling point | 373.4°C (rough estimate) | | density | 1.2117 (rough estimate) | | refractive index | 1.5447 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Benzene (Slightly, Heated, Sonicated), Chloroform (Slightly, Heated, Sonicated) | | form | Solid | | color | White to Off-White | | Water Solubility | Insoluble in water. | | BRN | 2055852 | | CAS DataBase Reference | 792-74-5(CAS DataBase Reference) | | NIST Chemistry Reference | [1,1'-Biphenyl]-4,4'-dicarboxylic acid, dimethyl ester(792-74-5) | | EPA Substance Registry System | [1,1'-Biphenyl]-4,4'-dicarboxylic acid, dimethyl ester (792-74-5) |
| | Biphenyl dimethyl dicarboxylate Usage And Synthesis |
| Chemical Properties | White or cream crystalline powder | | Uses | Dimethyl biphenyl-4,4'-dicarboxylate is used as a hepatoprotectant in the treatment of chronic hepatitis. At 250 μg/ml, it has been shown to stimulate JAK/STAT signaling and to induce the expression of interferon-α stimulated genes in a HepG2 cell line. It has been used to study hepatic fibrosis and chronic hepatocellular damage. It appears to normalize alanine aminotransferase (ALT) in cases where levels of ALT are elevated. It may be employed as starting reagent for the synthesis of dimethyl 2-fluoro-and 2,2?-difluorobiphenyl-4,4?-dicarboxylates. | | Synthesis Reference(s) | Tetrahedron Letters, 18, p. 4089, 1977 DOI: 10.1016/S0040-4039(01)83434-1 | | General Description | Dimethyl biphenyl-4,4′-dicarboxylate is a planar biphenyldicarboxylic acid ester. Crystal data of dimethyl biphenyl-4, 4′-dicarboxylate has been reported. |
| | Biphenyl dimethyl dicarboxylate Preparation Products And Raw materials |
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