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| Triphenylethylene Basic information |
| Triphenylethylene Chemical Properties |
Hazard Codes | Xn,N,Xi | Risk Statements | 22-36-50/53 | Safety Statements | 26-36/37-60-61 | RIDADR | UN 3077 9 / PGIII | WGK Germany | 3 | RTECS | KX4920000 | Hazard Note | Irritant | TSCA | Yes | HS Code | 29029080 |
| Triphenylethylene Usage And Synthesis |
Chemical Properties | White to slightly beige powder | Uses | Triphenylethylene is used in preparation of Esterase activated aggregation-induced luminescent anticancer prodrug. | Definition | ChEBI: Triphenylethylene is a stilbenoid. It is the core chemical structure of a number of related anti-estrogen compounds. The triphenylethylene antiestrogens, which include idoxifene, toremifene, chlorotrianisene, raloxifene and tamoxifen, act at the level of the estrogen receptor, triggering inhibition or stimulation of estrogen-dependent gene transcription and cellular physiology. | Synthesis Reference(s) | Journal of the American Chemical Society, 78, p. 82, 1956 DOI: 10.1021/ja01582a025 Organic Syntheses, Coll. Vol. 2, p. 606, 1943 Tetrahedron Letters, 14, p. 4193, 1973 | Safety Profile | Experimental
reproductive effects. Questionable
carcinogen with experimental tumorigenic
data. Human mutation data reported. When
heated to decomposition it emits acrid
smoke and irritating fumes. |
| Triphenylethylene Preparation Products And Raw materials |
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