3-Chloro-2-butanone

3-Chloro-2-butanone Basic information
Product Name:3-Chloro-2-butanone
Synonyms:3-CHLORO-2-BUTANONE;3-CL-MEK;1-CHLOROETHYL METHYL KETONE;1-ACETYL-1-CHLOROETHANE;3-chloro-2-butanon;3-Chloro-2-oxobutane~Methyl alpha-chloroethyl ketone;Chlorobutanone;3-CHLORO-2-BUTANONE, WACKER QUALITY
CAS:4091-39-8
MF:C4H7ClO
MW:106.55
EINECS:223-834-9
Product Categories:C3 to C6;Carbonyl Compounds;Ketones;ketone;API intermediates;Industrial/Fine Chemicals;Organics
Mol File:4091-39-8.mol
3-Chloro-2-butanone Structure
3-Chloro-2-butanone Chemical Properties
Melting point <-60°C
Boiling point 114-117 °C (lit.)
density 1.055 g/mL at 25 °C (lit.)
refractive index n20/D 1.421(lit.)
Fp 70 °F
storage temp. Flammables area
solubility 30g/l
form clear liquid
color Light orange to Yellow to Green
Specific Gravity1.058 (20/4℃)
PH2.4 (25g/l, H2O, 20℃)
explosive limit2.3%(V)
Water Solubility 3 g/100 mL
BRN 385637
CAS DataBase Reference4091-39-8(CAS DataBase Reference)
NIST Chemistry Reference2-Butanone, 3-chloro-(4091-39-8)
EPA Substance Registry System2-Butanone, 3-chloro- (4091-39-8)
Safety Information
Hazard Codes Xn
Risk Statements 10-22-36/37/38-20/21/22-2011/10/22
Safety Statements 16-36/37/39-26-24/25
RIDADR UN 1224 3/PG 3
WGK Germany 3
RTECS EL7062000
TSCA Yes
HazardClass 3
PackingGroup III
HS Code 29147090
MSDS Information
ProviderLanguage
3-Chloro-2-butanone English
SigmaAldrich English
ACROS English
ALFA English
3-Chloro-2-butanone Usage And Synthesis
Chemical PropertiesCLEAR YELLOW TO BROWNISH LIQUID
Uses3-Chloro-2-butanone was used in production of chiral alcohols from acetophenone derivatives, β-ketoesters and N-Boc-3-pyrrolidinone by recombinant E. coli cells. It was used in the synthesis of carbene precursor, 3-aryl-4,5-dimethylthiazolium chloride.
Uses3-Chloro-2-butanone was used to study various carbonylic compounds as substrates for 4-hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB.
Synthesis Reference(s)Journal of the American Chemical Society, 77, p. 5274, 1955 DOI: 10.1021/ja01625a016
General Description3-Chloro-2-butanone reacts with 1,4-dianion of acetophenone N-ethoxycarbonylhydrazone to yield pyrazoline derivatives.
3-Chloro-2-butanone Preparation Products And Raw materials
Preparation Products2,2'-BICINCHONINIC ACID-->Trimethyl thiazole-->3-(2-HYDROXY-PHENOXY)-BUTAN-2-ONE-->CHEMBRDG-BB 6141133-->3-(3-METHOXYPHENOXY)-2-BUTANONE-->3-(3-CHLOROPHENOXY)-2-BUTANONE-->AURORA 17336-->3-(3,5-DIMETHYLPHENOXY)-2-BUTANONE-->3-(4,5-DIMETHYL-THIAZOL-2-YL)-PHENYLAMINE
ETHYL 2-CHLORO-3-OXO-3-PHENYLPROPANOATE 1,3-Dibromo-1-chloro-2-butanone 2-CHLOROCYCLOOCTANONE 2-CHLOROCYCLOHEPTANONE 1-Chloro-2-Butanone 1,1-Dibromo-3-chloro-2-butanone 2-CHLORO-N,N-DIETHYLACETOACETAMIDE 2-CHLORO-3-OXO-N,3-DIPHENYLPROPANAMIDE 1-(4-Tert-Butylphenyl)-4-Chloro-1-Butanone N,N-DIMETHYL-2-CHLOROACETOACETAMIDE 2,2-DICHLORO-2,2A,7,7A-TETRAHYDRO-1H-CYCLOBUTA[A]INDEN-1-ONE 2,4'-DICHLOROPROPIOPHENONE tetrachlorocyclobut-2-enone 1-Chloro-2-butanone 4-[3,5-bis(trifluoromethyl)phenyl]-3-chloro-2-butanone chloro-2-butanone TETRACHLOROCYCLOPENTENE-1,3-DIONE 2,2,3,4,4-PENTACHLORO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-ONE

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