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| | DYCLONINE Basic information |
| Product Name: | DYCLONINE | | Synonyms: | DYCLONINE;1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanon;4’-butoxy-3-piperidino-propiophenon;dyclocaine;dyclonin;4'-Butoxy-β-piperidinopropiophenone;Dyclonine HCI;1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one | | CAS: | 586-60-7 | | MF: | C18H27NO2 | | MW: | 289.41 | | EINECS: | 1312995-182-4 | | Product Categories: | DYCLONE | | Mol File: | 586-60-7.mol |  |
| | DYCLONINE Chemical Properties |
| Boiling point | 424.5±25.0 °C(Predicted) | | density | 1.017±0.06 g/cm3(Predicted) | | pka | 8.68±0.10(Predicted) |
| | DYCLONINE Usage And Synthesis |
| Originator | Dyclone,Dow,US,1956 | | Uses | anesthetic (local) | | Definition | ChEBI: N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group. | | Manufacturing Process | A mixture of 17.6 grams of p-n-butoxyacetophenone, 12.1 grams of piperidine
hydrochloride, 4.5 grams paraformaldehyde, 0.25 cc concentrated hydrochloric
acid, 52.5 cc nitroethane, 7.5 cc of 95% ethanol, and 15 cc of toluene was
boiled under reflux for one hour, removing water formed in the reaction by
means of a condensate trap. The mixture was then cooled. The crystals which
formed were collected by filtration, washed with anhydrous ether and
recrystallized from methyl ethyl ketone. The crystals thus obtained, which
melted at 174-175°C, were shown by analysis to be 4-n-butoxy-β-
piperidinopropiophenone hydrochloride. | | Brand name | Dyclone (AstraZeneca). | | Therapeutic Function | Local anesthetic |
| | DYCLONINE Preparation Products And Raw materials |
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