MEGLUMINE DIATRIZOATE

MEGLUMINE DIATRIZOATE Basic information
Product Name:MEGLUMINE DIATRIZOATE
Synonyms:cardiografin;d-;d-glucitol,1-deoxy-1-(methylamino)-,3,5-bis(acetylamino)-2,4,6-triiodobenzo;diatrizoatemethylglucamine;gastrografin;glucitol,1-deoxy-1-(methylamino)-,3,5-diacetamido-2,4,6-triiodobenzoate(salt;hypaque13.4;hypaque60
CAS:131-49-7
MF:C18H26I3N3O9
MW:809.13
EINECS:205-024-7
Product Categories:Organics;Cell Separation (Centrifugation) Media;Hematology and Histology;amino acid
Mol File:131-49-7.mol
MEGLUMINE DIATRIZOATE Structure
MEGLUMINE DIATRIZOATE Chemical Properties
Melting point 189-193° (dec)
density 1.9465 (estimate)
storage temp. Refrigerator
solubility DMSO (Slightly), Water (Slightly)
form Solid
color Rhombic needles
Odorsltly sweet taste
InChIKeyMIKKOBKEXMRYFQ-KUAVVOKVNA-N
SMILESN(C1C(=C(NC(=O)C)C(I)=C(C(=O)O)C=1I)I)C(=O)C.[C@@H](O)([C@@H](O)CNC)[C@H](O)[C@H](O)CO |&1:20,22,27,29,r|
EPA Substance Registry SystemD-Glucitol, 1-deoxy-1-(methylamino)-, 3,5-bis(acetylamino)-2,4,6-triiodobenzoate (salt) (131-49-7)
Safety Information
WGK Germany 3
RTECS LZ4315000
ToxicityTDLo scu-man: 214 mg/kg 34ZIAG -,392,69
MSDS Information
MEGLUMINE DIATRIZOATE Usage And Synthesis
Chemical PropertiesAvailable in solution for injection, pH between 6.0–7.6.
UsesMedicine (radiopaque medium).
UsesMeglumine diatrizoate can be used to treat long-term Taenia saginata infection. It has also been used to tag fecal matter and bodily fluids in a study investigating preoperative examination techniques in patients with acute colon obstruction caused by colorectal cancer.
DefinitionChEBI: The N-methylglucamine salt of amidotrizoic acid. Both the sodium and the meglumine salts of amidotrizoic acid have been widely used as water-soluble radioopaque media in diagnostic radiography. The use of a mixture of the two salts is of en preferred, as adverse effects can be reduced.
Brand nameAngiovist (Berlex); Cardiografin (Bracco); Cystografin (Bracco); Hypaque (GE Healthcare); Reno (Bracco); Urovist (Berlex).
Safety ProfilePoison by intracerebral route.Human systemic effects by subcutaneous route: kidneydamage and reduced urine volume. When heated todecomposition it emits toxic fumes of I?? and NOx.
MEGLUMINE DIATRIZOATE Preparation Products And Raw materials
D-GLUCAMINE 4-IODO-3-METHYLANILINE 2-Iodobenzoic acid Diatrizoic Acid Dihydrate 1,3,5-TRIIODOBENZENE 4-IODOBENZALDEHYDE Acetrizoic acid 3-N-ETHYLAMINOACETANILIDE 4-Iodobenzoic acid 2-IODO-5-METHYLANILINE MEGLUMINE DIATRIZOATE 2,4-Diiodoaniline 3,5-bis(acetylamino)benzoic acid 3-acetamido-5-aminobenzoic acid adipiodone, dimeglumine salt N-(4-Iodophenyl)acetamide 3,5-diamino-2,4,6-triiodobenzoic acid DIATRIZOIC ACID

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