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| | 1,2,2,6,6-PENTAMETHYLPIPERIDINE Basic information |
| Product Name: | 1,2,2,6,6-PENTAMETHYLPIPERIDINE | | Synonyms: | PMP;PEMPIDINE;1,2,2,6,6-pentamethylenepiperidine;Pempidine, PMP;M and B-4486;1,2,2,6,6-Pentamethylpiperidine,95%;1,2,2,6,6-PentaMethylpiperidine, 95% 5GR;1,2,2,6,6-pentamethyl-piperidin | | CAS: | 79-55-0 | | MF: | C10H21N | | MW: | 155.28 | | EINECS: | 201-211-2 | | Product Categories: | API intermediates;Building Blocks;C10;Chemical Synthesis;Heterocyclic Building Blocks;Piperidines | | Mol File: | 79-55-0.mol |  |
| | 1,2,2,6,6-PENTAMETHYLPIPERIDINE Chemical Properties |
| Melting point | <25 °C | | Boiling point | 187-188 °C(lit.) | | density | 0.858 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.460(lit.) | | Fp | 122 °F | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Soluble in toluene, dimethylformamide. | | pka | 11.25(at 30℃) | | form | Liquid | | color | Clear colorless to light yellow | | Sensitive | Air Sensitive | | Merck | 14,7080 | | BRN | 103806 | | InChIKey | XULIXFLCVXWHRF-UHFFFAOYSA-N | | CAS DataBase Reference | 79-55-0(CAS DataBase Reference) | | EPA Substance Registry System | Piperidine, 1,2,2,6,6-pentamethyl- (79-55-0) |
| Hazard Codes | Xn | | Risk Statements | 10-22-36/37/38 | | Safety Statements | 26-36/37 | | RIDADR | UN 1992 3/PG 3 | | WGK Germany | 3 | | RTECS | TN2190000 | | F | 10-34 | | TSCA | Yes | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29333999 | | Toxicity | LD50 orl-mus: 275 mg/kg NATUAS 184,1707,59 |
| | 1,2,2,6,6-PENTAMETHYLPIPERIDINE Usage And Synthesis |
| Chemical Properties | CLEAR COLORLESS TO LIGHT YELLOW LIQUID | | Uses | ganglionic blocker, antihypertensive | | Uses | 1,2,2,6,6-Pentamethylpiperidine is used in the synthesis of BN-fused polycyclic aromatic molecules for potential application to electronic materials and apparatus. In addition, it is a catalyst for th
e chemoselective silylation of benzylic alcohols. | | Uses | Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine's ED50 4.7-fold. | | Definition | ChEBI: 1,2,2,6,6-pentamethylpiperidine is a member of piperidines. | | General Description | The focal 1,8-naphthalimide fluorophores in the antennae were modified with 1,2,2,6,6-pentamethylpiperidine to improve their photostability. | | Safety Profile | Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx. |
| | 1,2,2,6,6-PENTAMETHYLPIPERIDINE Preparation Products And Raw materials |
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