1-CHLORO-3-METHOXY-2-PROPANOL

1-CHLORO-3-METHOXY-2-PROPANOL Basic information
Product Name:1-CHLORO-3-METHOXY-2-PROPANOL
Synonyms:1-CHLORO-3-METHOXY-2-PROPANOL;3-CHLORO-1-METHOXY-2-PROPANOL;3-CHLORO-2-HYDROXYPROPYL METHYL ETHER;1-Methoxy-3-chloro-2-propanol;3-CHLORO-1-METHOXY-2-PROPANOL FOR SYNTHE;3-Chloro-1-methoxy-2-propanol for synthesis;2-Propanol, 1-chloro-3-methoxy-;1-CHLORO-3-METHOXY-2-PROPANOL 98+%
CAS:4151-97-7
MF:C4H9ClO2
MW:124.57
EINECS:223-982-4
Product Categories:
Mol File:4151-97-7.mol
1-CHLORO-3-METHOXY-2-PROPANOL Structure
1-CHLORO-3-METHOXY-2-PROPANOL Chemical Properties
Boiling point 171°C
density 1,161 g/cm3
refractive index 1.4463
Fp 72°C
storage temp. Store below +30°C.
solubility Chloroform, DMSO (Sparingly), Methanol (Slightly)
form Oily Liquid
pka13.28±0.20(Predicted)
color Clear faintly yellow
PH5.6 (50g/l, H2O)
BRN 1697491
Safety Information
Hazard Codes Xi
Risk Statements 20/21/22-36-36/37/38
Safety Statements 23-26-36/37/39-36
RIDADR 2810
WGK Germany WGK 3 highly water endangering
HS Code 2909 49 80
PackingGroup III
ToxicityLD50 orally in Rabbit: 340 mg/kg
MSDS Information
ProviderLanguage
ALFA English
1-CHLORO-3-METHOXY-2-PROPANOL Usage And Synthesis
Chemical PropertiesClear faintly yellow oily liquid
Uses1-Chloro-3-methoxy-2-propanol is used in the synthesis of O-Methylganciclovir (M275440), an analogue of Ganciclovir (G235000) and displays excellent antiviral activity when tested in vivo against herpes simplex virus type 1 infection in mice.
Synthesis Reference(s)The Journal of Organic Chemistry, 53, p. 275, 1988 DOI: 10.1021/jo00237a009
Synthetic Communications, 24, p. 1959, 1994 DOI: 10.1080/00397919408010203
1-CHLORO-3-METHOXY-2-PROPANOL Preparation Products And Raw materials
4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE ALPHA-ACETOCHLORO-D-FRUCTOSE 1,3-Dioxolan-2-one, 4-(chloromethyl)- AURORA KA-6999 2,3,4-TRI-O-ACETYL-ALPHA-D-XYLOPYRANOSYL CHLORIDE 3-CHLORO-2,4-DIHYDROXY-5-OXO-2-TETRAHYDROFUROIC ACID 2-(CHLOROMETHYL)-2,3-DIHYDRO-1,4-BENZODIOXINE 2,2',3,3',4',5,6'-HEPTA-O-ACETYL-ALPHA-D-CELLOBIOSYL CHLORIDE 3-CHLORO-2-ETHOXY-4-HYDROXY-5-OXO-2-TETRAHYDROFUROIC ACID ETHYL ETHER 3-CHLORO-2-HYDROXYPROPYL METHACRYLATE 2-HYDROXY-3-CHLOROPROPYL ACRYLATE 2'-CHLORO-2'-DEOXYURIDINE 1-ALLYLOXY-3-CHLORO-2-PROPANOL 6-CHLORO-6-DEOXY-D-MANNOSE 2,3,4,6-TETRA-O-ACETYL-BETA-D-GLUCOPYRANOSYL CHLORIDE 4-ACETOXY-3-CHLORO-2-ETHOXY-5-OXO-2-TETRAHYDROFUROIC ACID ETHYL ETHER 2,3,4,6-TETRA-O-ACETYL-ALPHA-D-GALACTOPYRANOSYL CHLORIDE 1-(ALPHA-NAPHTHOXY)-3-CHLORO-2-PROPANOL

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