2'-Deoxycytidine

2'-Deoxycytidine Basic information
Product Name:2'-Deoxycytidine
Synonyms:DC;CYTOSINE DEOXYRIBOSIDE;1-(2'-DEOXY-BETA-D-RIBOFURANOSYL)CYTOSINE;2'-DC;2'-DEOXY-D-CYTIDINE;2'-DEOXYCYTIDINE;4-Amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;2'-DEOXYCYTIDINE:H2O
CAS:207121-53-7
MF:C9H15N3O5
MW:245.24
EINECS:213-454-1
Product Categories:Miscellaneous Biochemicals
Mol File:207121-53-7.mol
2'-Deoxycytidine Structure
2'-Deoxycytidine Chemical Properties
Melting point 209-211 °C(lit.)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Methanol (Slightly), Water (Slightly)
form Solid
color White
Stability:Hygroscopic
InChIInChI=1/C9H13N3O4.H2O/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8;/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15);1H2/t5-,6+,8+;/s3
InChIKeyHXBGOHZLZCFWLH-AZXCMKNYNA-N
SMILESO=C1N=C(N)C=CN1[C@H]1C[C@H](O)[C@@H](CO)O1.O |&1:8,10,12,r|
Safety Information
WGK Germany 3
RTECS HA3800000
10
MSDS Information
ProviderLanguage
SigmaAldrich English
2'-Deoxycytidine Usage And Synthesis
UsesA deoxyribonucleoside as Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity.
DefinitionChEBI: 2'-deoxycytidine is a pyrimidine 2'-deoxyribonucleoside having cytosine as the nucleobase. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a cytosine.
Purification MethodsPurify 2'-deoxycytidine by recrystallisation from MeOH/Et2O or EtOH and dry it in air. [NMR: Miles J Am Chem Soc 85 1007 1963, UV: Fox & Shugar Biochim Biophys Acta 9 369 1952.] The hydrochloride crystallises from H2O/EtOH and has m 174o(dec, 169-173o). [Walker & Butler Can J Chem 34 1168 1956.] The picrate has m 208o(dec). [Fox et al. J Am Chem Soc 83 4066 1961, Beilstein 25 III/IV 3662.]
2'-Deoxycytidine Preparation Products And Raw materials
Cytidine-5'-triphosphate disodium salt dihydrate Zalcitabine Cytidine 5’-monophosphate Floxuridine Cytosine ALTRENOGEST 5-Azacytidine 6-Aminocaproic acid Glycine 5-Aza-2'-deoxycytidine Cytarabine Fluorocytosine deoxycytidin Cytidine Tris(hydroxymethyl)aminomethane AMINO ACIDS 5-Fluorocytidine CHLOROPHOSPHONAZO III

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