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| (R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Basic information |
Product Name: | (R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER | Synonyms: | (R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER;BOC-D-PRO(4-OXO);N-BOC-4-OXO-D-PROLINE;N-Boc-4-oxo-D-proline Methyl ester;1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1-(1,1-diMethylethyl) ester, (2R)-;(R)-1-(tert-Butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid;(2R)-N-Boc-4-oxo-proline;(2R)-1-[(tert-butoxy)carbonyl]-4-oxopyrrolidine-2-carboxylic acid | CAS: | 364077-84-9 | MF: | C10H15NO5 | MW: | 229.23 | EINECS: | | Product Categories: | pharmacetical | Mol File: | 364077-84-9.mol | |
| (R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Chemical Properties |
Boiling point | 390.8±42.0 °C(Predicted) | density | 1.304±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,Room Temperature | pka | 3.85±0.20(Predicted) |
| (R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Usage And Synthesis |
Uses | (2R)-N-Boc-4-oxo-proline was used as a reactant in the preparation of 4,4-disubstituted pyrrolidine-1,2-dicarboxamides which are potent factor Xa inhibitors with increased human half life. Also used in the synthesis of azacyclic FTY720 analogues which show potential for use in strategy to kill cancer cells as they restrict access to extracellular nutrients. |
| (R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Preparation Products And Raw materials |
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