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| | Copper(II) gluconate Chemical Properties |
| Melting point | 155-157 °C(lit.) | | Boiling point | 673.6℃[at 101 325 Pa] | | density | 1.777[at 20℃] | | vapor pressure | 13.3Pa at 20℃ | | refractive index | 16.5 ° (C=1, H2O) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Aqueous Acid (Slightly), Water (Sparingly, Sonicated) | | form | powder | | color | Light Blue to Blue | | optical activity | [α]26/D +15°, c = 1 in H2O | | Water Solubility | slightly soluble | | Merck | 14,2640 | | Exposure limits | ACGIH: TWA 1 mg/m3
NIOSH: IDLH 100 mg/m3; TWA 1 mg/m3 | | Stability: | Hygrscopic | | LogP | -2.98 | | CAS DataBase Reference | 527-09-3(CAS DataBase Reference) | | EPA Substance Registry System | Copper gluconate (527-09-3) |
| | Copper(II) gluconate Usage And Synthesis |
| Description | Copper(II) gluconate is the copper salt of D-gluconic acid that is an organic acid. It can be used as a buffer for encapsulating some drugs into liposomes. Copper is an essential microelement for human beings and animals; it is needed to absorb ion from and gut and can help regulate blood pressure and heart rate. It is also a key component of multiple enzymes involved in many biochemical reactions. In this sense, the D-gluconic acid copper (II) salt can be used as a copper supplement to treat the copper deficiency induced anemia and nephrosis. It is also useful in the cancer chemotherapy being capable of enhancing the efficacy of the anticancer drug, disulfiram. | | References | Dicko, Awa, et al. "Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes." International Journal of Pharmaceutics 337.1(2007):219-228.
Ferris Iii, Frederick L, et al. "Nutritional supplement to treat macular degeneration.", EP1516542. 2009.
Georgewill Udeme Owunari, Siminialayi Iyeopu Minakiri. “Disulfiram and Copper gluconate in cancer chemotherapy: a review of the literature.” Cancer Research Journal 2.5(2014):88-92.
| | Chemical Properties | Copper(II) gluconate, Cu(C6H11O7)2, is a light blue to blue-green, crystalline material that is soluble in water and slightly soluble in ethanol. | | Uses | Supplement (trace mineral). | | Uses | copper gluconate is cited as having skin-conditioning and skinprotecting functions. | | Uses | Copper(II) gluconate is used in dietary supplement. It is also used to treat acne vulgaris, common cold, hypertension, premature labor, leishmaniasis and visceral postoperative complications. Further, it is used in oral deodorants and feed additives. In addition to this, it is used as a synergist and nutritional supplement for foods. It is the active component in retsyn used in mints and certs. | | Preparation | Copper(II) gluconate is prepared by the dissolution of copper(II) carbonate or copper(II) hydroxide in gluconic acid. It is used as a nutritional supplement for copper deficiency and as a component in oral deodorants. | | Definition | ChEBI: Copper gluconate is an organic molecular entity. | | Flammability and Explosibility | Notclassified | | Safety Profile | When heated to
decomposition it emits acrid smoke and
irritating fumes. |
| | Copper(II) gluconate Preparation Products And Raw materials |
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