ChemicalBook Product Catalog Pharmaceutical intermediates Bulk Drug Intermediates 4-Cloromethyl-5-methyl-1,3-dioxol-2-one

4-Cloromethyl-5-methyl-1,3-dioxol-2-one

4-Cloromethyl-5-methyl-1,3-dioxol-2-one Basic information
Product Name:4-Cloromethyl-5-methyl-1,3-dioxol-2-one
Synonyms:DMDO-CL;4-Cloromethyl-5-methyl-1,3-dioxol-2-one;Olmesartan Impurity 57;4-CloroMethyl-5-Methyl-1,3-dioxol-2-one (DMDO-Cl);OlMesartan IMpurity (4-(ChloroMethyl)-5-Methyl-1,3-Dioxol-2-one);4- chloroMethyl-5- Methyl-1,3- two oxygenheterocyclicpentadiene-2- ketone;-5--1,3- two4-chloroMethylMethylcyclopentene-2- ketoneheterocyclic oxygen;4-ChloroMethyl-5-Methyl-l,3-dioxocyclopenten-2–one
CAS:80841-78-7
MF:C5H5ClO3
MW:148.54
EINECS:617-178-6
Product Categories:Carbonates;Carbonyl Compounds;Chemical intermediate for Olmesartane;INTERMEDIATESOF;Organic Building Blocks;Pharmaceutical Intermediates
Mol File:80841-78-7.mol
4-Cloromethyl-5-methyl-1,3-dioxol-2-one Structure
4-Cloromethyl-5-methyl-1,3-dioxol-2-one Chemical Properties
Boiling point >90℃/2mm
density 1.362±0.06 g/cm3(Predicted)
refractive index 1.4760-1.4820
Fp 129 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Oil
color Light Yellow to Very Dark Brown
BRN 4798926
InChIKeyQCLFSYYUWPUWQR-UHFFFAOYSA-N
CAS DataBase Reference80841-78-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26
WGK Germany 3
HS Code 29329990
MSDS Information
4-Cloromethyl-5-methyl-1,3-dioxol-2-one Usage And Synthesis
Chemical PropertiesColorless to Light yellow to Light orange clear liquid or Pale Yellow Oil.
Uses4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). It is also used in the preparation of prodrugs of ampicillin.
4-Cloromethyl-5-methyl-1,3-dioxol-2-one Preparation Products And Raw materials
Preparation ProductsTrityl olmesartan-->Trityl Olmesartan Medoxomil
4,5-Dimethyl-1,3-dioxol-2-one Methylparaben Methyl N-Methyl-2-pyrrolidone Bensulfuron methyl Norgestrel Mesotrione Methyl cellulose tert-Butyldimethylsilyl chloride 4-Cloromethyl-5-methyl-1,3-dioxol-2-one Kresoxim-methyl 4-Bromomethyl-5-methyl-1,3-dioxol-2-one Methanol Methyl acrylate 4-Methyl-2-pentanone Vinylene carbonate Methyl bromide METSULFURON METHYL
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