2-Chloro-5-fluoropyridine

2-Chloro-5-fluoropyridine Basic information

Product Name:	2-Chloro-5-fluoropyridine
Synonyms:	2-CHLORO-5-FLUOROPYRIDINE;2-Chloro-5-fluoropyridine 98%;2-Chloro-5-fluoropyridine98%;2-Chloro-5-fluoropyridine ,96%;2-chloro-5-fluoridepyridine;5-Fluoro-2-chloropyridine;2-CHLORO-5-FLUOROPYPRIDINE;Pyridine, 2-chloro-5-fluoro-
CAS:	31301-51-6
MF:	C5H3ClFN
MW:	131.54
EINECS:
Product Categories:	Pyridines derivates;Chloropyridines;Pyridine;pyridine derivative;Fluoropyridines;Halopyridines;Fluorin-contained pyridine series;Pyridines, Pyrimidines, Purines and Pteredines;Pyridines;Boronic Acid;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Variety of halogenated heterocyclic series;Building Blocks;C5;C5 to C6;Chemical Synthesis;Fluorinated Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles;Fluorine series;bc0001
Mol File:	31301-51-6.mol

2-Chloro-5-fluoropyridine Chemical Properties

Melting point	19℃
Boiling point	74 °C / 38mmHg
density	1.297 g/mL at 25 °C
refractive index	n20/D 1.503
Fp	108 °C
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	powder to lump to clear liquid
pka	-2.20±0.10(Predicted)
color	White or Colorless to Light yellow
InChIKey	QOGXQLSFJCIDNY-UHFFFAOYSA-N
CAS DataBase Reference	31301-51-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	10-22-37/38-41-36/37/38
Safety Statements	26-36/39-36
RIDADR	UN 1993 3/PG 3
WGK Germany	3
Hazard Note	Irritant
HazardClass	3
PackingGroup	III
HS Code	29339900

MSDS Information

Provider	Language
SigmaAldrich	English

2-Chloro-5-fluoropyridine Usage And Synthesis

Chemical Properties	Light yellow powder
Uses	2-Chloro-5-fluoropyridine, is the intermediate used for the synthesis of pharmaceuticals agents and biologically active compounds, such as pyrazol-3-ylamino pyrazines as novel JAK2 inhibitors.

2-Chloro-5-fluoropyridine Preparation Products And Raw materials

Raw materials	Fluoroboric acid-->Heptane-->Isoamyl nitrite-->5-Amino-2-chloropyridine
Preparation Products	2-Cyano-5-fluoropyridine-->N-(2-chloro-5-luoropyridin-4-yl)nitraMide-->6-chloro-3-fluoro-2-methoxyPyridine

2,6-DICHLORO-5-FLUORO-N-(2-THIENYLMETHYL)NICOTINAMIDE (2,6-DICHLORO-5-FLUOROPYRIDIN-3-YL)(PIPERIDINO)METHANONE 2,6-DICHLORO-5-FLUORO-N-ISOPROPYLNICOTINAMIDE 2,6-DICHLORO-5-FLUORO-N-PHENYLNICOTINAMIDE 2-Chloro-3-cyanopyridine 2,6-DICHLORO-N-(4-CHLOROPHENYL)-5-FLUORONICOTINAMIDE 2-Chloro-5-chloromethylpyridine 2,6-Dichloro-5-fluoronicotinic acid 2-Chloro-5-fluoropyridine 3-Pyridinemethanol, 2-chloro-alpha-((2-(dimethylamino)ethoxy)methyl)-5 -fluoro-6-(methylamino)-, monohydrochloride Difluorochloromethane 2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile N-[4-(TERT-BUTYL)PHENYL]-2,6-DICHLORO-5-FLUORONICOTINAMIDE 2,6-DICHLORO-5-FLUORONICOTINAMIDE ETHYL 3-(2,6-DICHLORO-5-FLUOROPYRIDIN-3-YL)-3-OXOPROPANOATE 3-METHOXYPHENYL 2,6-DICHLORO-5-FLUORONICOTINATE 2,6-DICHLORO-5-FLUORONICOTINOYL CHLORIDE (2,6-DICHLORO-5-FLUOROPYRIDIN-3-YL)(MORPHOLINO)METHANONE

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