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| | 19-O-Acetylchaetoglobosin A Basic information |
| Product Name: | 19-O-Acetylchaetoglobosin A | | Synonyms: | 19-O-Acetylchaetoglobosin A;12H-Cyclotridec[d]oxireno[f]isoindole-8,11,12-trione, 7-(acetyloxy)-3,4,7,13,14,14a,15,15a,16a,16b-decahydro-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-, (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)- (9CI);Chaetoglobosin A Acetate | | CAS: | 50939-69-0 | | MF: | C34H38N2O6 | | MW: | 570.68 | | EINECS: | | | Product Categories: | | | Mol File: | 50939-69-0.mol |  |
| | 19-O-Acetylchaetoglobosin A Chemical Properties |
| Boiling point | 781.3±60.0 °C(Predicted) | | density | 1.29±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | form | A solid | | pka | 17.32±0.30(Predicted) |
| | 19-O-Acetylchaetoglobosin A Usage And Synthesis |
| Biological Activity | 19-O-Acetylchaetoglobosin A is a fungal metabolite originally isolated from C. globosum that has actin polymerization inhibitory and cytotoxic activities.1,2 It inhibits actin polymerization in a cell-free assay when used at a concentration of 2 μM.2 19-O-Acetylchaetoglobosin A (3.2, 10, and 32 μg/ml) is cytotoxic to HeLa cervical cancer cells.1 | | References | 1.Umeda, M., Ohtsubo, K., Saito, M., et al.Cytotoxicity of new cytochalasans from Chaetomium globosumExperientia31(4)435-438(1975)
2.Sekita, S., Yoshihira, K., Natori, S., et al.Structure-activity relationship of thirty-nine cytochalasans observed in the effects on cellular structures and cellular events and on actin polymerization in vitroJ. Pharmacobiodyn.8(11)906-916(1985)
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| | 19-O-Acetylchaetoglobosin A Preparation Products And Raw materials |
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