ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Methylpyridine 2-Fluoro-4-methylpyridine

2-Fluoro-4-methylpyridine

2-Fluoro-4-methylpyridine Basic information
Product Name:2-Fluoro-4-methylpyridine
Synonyms:2-FLUORO-4-METHYLPYRIDINE;2-FLUORO-4-PICOLINE;2-FLUORO-4-METHYLPYRIDINE 98%;2-Fluoro-4-methylpyridine/2-Fluoro-4-Picoline;2-Fluoro-4-methylpyridine97%;2-FLUORO-4-METHYLPYRIDINE, 99+%;2-FLUORO-4-PICOLINE 2-FLUORO-4-METHYLPYRIDINE;2-Fluoro-4-mehtylpyridine
CAS:461-87-0
MF:C6H6FN
MW:111.12
EINECS:625-585-5
Product Categories:Fluorinated heterocyclic series;Fluoropyridines;Halides;Pyridines;Halopyridines;Boronic Acid;Pyridine;Pyridines, Pyrimidines, Purines and Pteredines
Mol File:461-87-0.mol
2-Fluoro-4-methylpyridine Structure
2-Fluoro-4-methylpyridine Chemical Properties
Boiling point 160-161 °C (lit.)
density 1.078 g/mL at 25 °C (lit.)
refractive index n20/D 1.472(lit.)
Fp >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Liquid
pka0.24±0.10(Predicted)
Specific Gravity1.078
color Colorless to pale yellow
BRN 107086
InChIKeyZBFAXMKJADVOGH-UHFFFAOYSA-N
CAS DataBase Reference461-87-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR 1993
WGK Germany 3
Hazard Note Irritant
HazardClass 3
PackingGroup III
HS Code 29333990
MSDS Information
ProviderLanguage
2-Fluoro-4-methylpyridine English
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2-Fluoro-4-methylpyridine Usage And Synthesis
Chemical PropertiesClear colourless to light yellow liquid
Uses2-Fluoro-4-methylpyridine may be used in the preparation of:
  • 2-Fluoro-4-(iodomethyl)pyridine
  • 4-(4-fluorophenyl)-5-(2-fluoropyridin-4-yl)-1,3-dihydroimidazol-2-thione
  • 2-fluoro-4-pyridinemethanol
  • 2-fluoro-4-pyridinemethanol, 4-methylbenzenesulfonate
  • 10,10-bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone
  • 2-fluoro-3-iodo-5-methylpyridine
  • 2-fluoro-4-pyridinecarboxylic acid

General Description2-Fluoro-4-methylpyridine, also known as 2-fluoro-4-picoline, can be prepared based on Talik′s procedure from 2-amino-5-methylpyridine via diazotization. The effect of substituents on spectral properties of 2-fluoro-6-methylpyridine has been investigated based on 13C NMR, UV and IR spectral data.
2-Fluoro-4-methylpyridine Preparation Products And Raw materials
Preparation Products2-Fluoropyridine-4-carboxaldehyde-->(2-FLUORO-PYRIDIN-4-YL)-HYDRAZINE-->Methyl 2-Fluoroisonicotinate-->2-Methyl-2-(4-methylpyridin-2-yl)propanenitrile
2-Fluoro-beta-oxo-4-pyridinepropanoicacidethylester (2,3,5,6-TETRAFLUORO-4-PYRIDINYL)ACETIC ACID 2-AMINO-3,6-DIFLUORO-4-(TRIFLUOROMETHYL)PYRIDINE Fluorine 2-AMINO-3,5,6-TRIFLUORO-PYRIDINE-4-CARBOXAMIDE 2-Chloro-5-chloromethylpyridine 1-(2-Fluoro-3-(2-propenyl)-4-pyridinyl)-1-propanone 2,3,5,6-TETRAFLUOROPYRIDINE-4-CARBOXYLIC ACID 4-Methylpyridine 6-fluoropyridoxal 2-Fluoro-4-methyl-5-nitropyridine 2-Fluoro-4-methylpyridine Azamethiphos 2,3,5-TRIFLUOROPYRIDINE-4-CARBOXYLIC ACID, 97 2,6-Lutidine 2,3,6-TRIFLUORO-4-(TRIFLUOROMETHYL)PYRIDINE 2,3,6-TRIFLUOROISONICOTINIC ACID 5-AMINO-2-FLUORO-ISONICOTINIC ACID
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