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| | Cresol Red Basic information |
| Product Name: | Cresol Red | | Synonyms: | Phenol, 4,4-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis2-methyl-;Cresol Red;Cresol Red, Indicator grade, pure 25GR;Cresol Red, Indicator grade, pure 5GR;Cresol Red (0.1% in ca. 20% Ethanol) [for Titration];3,3-Bis(3-methyl-4-hydroxyphenyl)-3H-2,1-benzoxathiole 1,1-dioxide;Cresol Red,pure,Indicator grade;o-Cresol Red p.a. (green powder) | | CAS: | 1733-12-6 | | MF: | C21H18O5S | | MW: | 382.43 | | EINECS: | 217-064-2 | | Product Categories: | Organics;Analytical Chemistry;Indicator (pH);pH Indicators;Sulfonephthalein;bulk reagents | | Mol File: | 1733-12-6.mol |  |
| | Cresol Red Chemical Properties |
| Melting point | 290 °C | | Boiling point | 479.59°C (rough estimate) | | density | 0.998 g/cm3 | | refractive index | 1.5300 (estimate) | | storage temp. | Store at +5°C to +30°C. | | solubility | Solubility Sparingly soluble in water; soluble in ethanol | | form | Powder | | pka | 1.0(at 25℃) | | color | Dark green or brown-red | | PH | 7.2～8.8 | | PH Range | 7.2(YELLOW)--8.8(PURPLISH RED) | | Water Solubility | soluble | | λmax | 570nm, 367nm, 432nm | | Merck | 14,2578 | | BRN | 343399 | | Major Application | Display device, optical sensors, combustion gas detection system, inks, correction fluid, diapers, toothpaste, identifying fresh and stale rice, food storage, determine glucose in dialysis solution, monitor metabolic activity of microorganisms, detect bacterialinfection, psychoactive drugs, dental impression material | | InChIKey | ASMGMVUGPNODGX-UHFFFAOYSA-N | | EPA Substance Registry System | Cresol Red (1733-12-6) |
| Hazard Codes | Xi,Xn,F | | Risk Statements | 36/37/38-20/21/22-11 | | Safety Statements | 24/25-36-26-16 | | RIDADR | UN1170 - class 3 - PG 3 - Ethanol, solution | | WGK Germany | 3 | | TSCA | Yes | | HS Code | 29349990 | | Toxicity | A potent lacrimator
which is chemically stable and retains its irritancy in water
and so can be used in liquid jets in personnel control. In addition
to lacrimation, it causes eye pain, blepharospasm, eyelid
swelling, irritation of the conjunctiva, a rise in intraocular
pressure, and erythema of the skin. Because it can be used in
water, its use is less affected by changes in climatic conditions.
It is a more potent lacrimator than CS but it is less potent in
lethality than CS. |
| | Cresol Red Usage And Synthesis |
| Chemical Properties | Dark green or brown-red powder | | Uses | Acid-base indicator. | | Uses | Cresol red is commonly used with lead acetate for the detection of urease after PAGE. It is also used as an indicator with the following transition intervals: pH 1.8 (orange) to pH 2.0 (yellow); pH 7.0 (yellow) to pH 8.8 (violet). Cresol Red is used as a tracking dye in DNA, RNA (agarose) and protein (polyacrylamide) electrophoresis. In agarose, Cresol Red runs with an apparent molecular size of approx. 125 bp DNA. Cresol Red does not inhibit Taq polymerase. | | Definition | ChEBI: A member of the class of 2,1-benzoxathioles that is 2,1-benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxy-5-methylphenyl groups. | | Purification Methods | Crystallise it from glacial acetic acid. Dry it in air. Dissolve it in aqueous 5% NaHCO3 solution and precipitate it from a hot solution by dropwise addition of aqueous HCl. Repeat the procedure till the UVmax does not increase. [Beilstein 19 IV 1133.] |
| | Cresol Red Preparation Products And Raw materials |
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