ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Other Amino Acid Protection L-Prolinamide

L-Prolinamide

L-Prolinamide Basic information
Product Name:L-Prolinamide
Synonyms:H-Pro-NH2≥ 99.5% (HPLC, Chiral purity);L-Prolinamide,99%e.e.;L-PROLINAMIDE FREE BASE;L-PROLINAMIDE 99.0%;H-Pro-NH2, free base;L-Srolinamide, 98%;L-Pro-NH2;L-Prolinamide,98%
CAS:7531-52-4
MF:C5H10N2O
MW:114.15
EINECS:231-397-0
Product Categories:APIs;Amino Acids;Amino Acid Derivatives;Peptide Synthesis;Proline;Proline [Pro, P];Amino Acids and Derivatives;Amides (Chiral);Chiral Building Blocks;Synthetic Organic Chemistry;Miscellaneous Reagents;Aromatics;Catalyst;Heterocycles;AMINOACIDS DERIVATIVES;API;Pharmaceuticalintermediates;7531-52-4
Mol File:7531-52-4.mol
L-Prolinamide Structure
L-Prolinamide Chemical Properties
Melting point 95-97 °C (lit.)
alpha -106 º (c=2, EtOH)
Boiling point 213.66°C (rough estimate)
density 1.1008 (rough estimate)
refractive index 1.4720 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Powder or Granules
pka16.21±0.20(Predicted)
color White to straw
optical activity[α]20/D 106°, c = 2 in ethanol
Water Solubility Soluble in water and ethanol (50 mg/ml).
BRN 80807
InChIKeyVLJNHYLEOZPXFW-BYPYZUCNSA-N
CAS DataBase Reference7531-52-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 22-24/25-36/37/39-26
WGK Germany 3
F 10
HS Code 29339900
MSDS Information
ProviderLanguage
L-Prolinamide English
SigmaAldrich English
ACROS English
ALFA English
L-Prolinamide Usage And Synthesis
Chemical PropertiesCrystalline
UsesProline based organocatalyst.
UsesIt is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. Also it is a efficient organocatalysts for aldol reactions on water.
DefinitionChEBI: The carboxamide derivative of L-proline.
L-Prolinamide Preparation Products And Raw materials
Preparation Products2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI)-->Z-PRO-NH2-->D-1-N-Boc-prolinamide-->Pyrrolidine, 2-(methylaminomethyl)--->2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)- (9CI)-->(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
N-(tert-butoxycarbonyl)-4-nitro-3-phenyl-L-alanyl-L-prolinamide N-BENZYLOXYCARBONYL-N'-ETHYL-L-PROLINAMIDE L-(-)-PROLINAMIDE HYDROCHLORIDE,L-PROLINAMIDE HCL,L-PROLINAMIDE HYDROCHLORIDE N-(tert-butoxycarbonyl)-D-methionylglycyl-4-nitro-3-phenyl-L-alanyl-L-prolinamide 5-oxo-L-propyl-L-prolinamide N-(tert-butoxycarbonyl)-L-tyrosyl-D-methionylglycyl-4-nitro-3-phenyl-L-alanyl-L-prolinamide (S)-2-THIOCARBAMOYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER N-T-BOC-4,4-DIFLUORO-L-PROLINAMIDE,BOC-4,4-DIFLUORO-L-PROLINAMIDE (R)-2-THIOCARBAMOYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER LEUPROLIDE = 5-OXO-L-PROLIL-L-HISTIDIL-L-TRYPTOPHIL-L-SERIL-L-THYROZIL-D-LEUCIL-L-ARGINIL-N-ETHYL-L-PROLINAMIDE 5-OXO-N-[3-(TRIFLUOROMETHYL)PHENYL]PROLINAMIDE N-(2-NAPHTHYL)-L-PROLINAMIDE HYDROCHLORIDE BENZYLOXYCARBONYL-L-PROLINAMIDE,(S)-1-N-CBZ-PROLINAMIDE,Z-L-PROLINAMIDE,N-BENZYLOXYCARBONYL-L-PROLINAMIDE,CARBOBENZYLOXY-L-PROLINAMIDE,CBZ-L-PROLINAMIDE Luteinizing hormone-releasing factor (pig), 6-[3-(ethylthio)-d-valine]-9-(N-ethyl-l-prolinamide)-10-deglycinamide- (n-ethyl-l-prolinamide)-10-deglycinamide Transglutaminase Boc-D-Glutamine PROLINAMIDOETHYL IMIDAZOLE
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