6-METHYLMERCAPTOPURINE RIBOSIDE Usage And Synthesis
Chemical Properties
white powder
Uses
6-Methylmercaptopurine Riboside (cas# 342-69-8) is a compound useful in organic synthesis.
Uses
6-Methylmercaptopurine riboside (6MMPr) is used in studies on thiopurine metabolism by enzymes such as inosine-5′-monophosphate dehydrogenase and thiopurine methyltransferase. 6MMPr may also be used to study mechanisms of bovine viral diarrhea virus (BVDV) inhibition.
Definition
ChEBI: A thiopurine that is inosine in which the aromatic hydroxy group is replaced by a methylsulfanediyl group.
General Description
White powder.
Air & Water Reactions
Slightly soluble in water.
Biochem/physiol Actions
6-Methylmercaptopurine riboside (6MMPR) is a modified thiopurine nucleoside involved in the inhibition of purine synthesis. It exhibits anti-viral effects against various viruses. 6MMPR is an analog of purine and an inhibitor of nerve growth factor-activated protein kinase N.
Safety Profile
Poison by
intraperitoneal route. Experimental
teratogenic effects. Questionable carcinogen
with experimental tumorigenic data.
Mutation data reported. When heated to
decomposition it emits very toxic fumes of
SO, and NOx.
6-METHYLMERCAPTOPURINE RIBOSIDE Preparation Products And Raw materials
