TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE

TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE Basic information
Reactions
Product Name:TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE
Synonyms:Phosphine, tricyclohexyl-, tetrafluoroborate(1-)(1:1);TRICYCLOHEXYLPHOSPHONIUM TETRA;TricyclohexylphosphoniuM tetrafluoroborate,Cy3PH+BF4-;Tricyclohexylphosphine tetrafluoroborate 97%;TricyclohexylphosphoniuM tetrafluoroborate, 98%, 98%;Tricyclohexylphosphonium tetrafluoroborate,98% Cy3PH+BF4-;Tricyclohexylphosphoniumtetrafluoroborate,99%;Tricyclohexylphosphine tetrofluroborate
CAS:58656-04-5
MF:C18H34BF4P
MW:368.24
EINECS:672-607-4
Product Categories:Achiral Phosphine;Alkyl Phosphine;P-BF4;organophosphine salt;Basic Phosphine LigandsCatalysis and Inorganic Chemistry;Catalysis and Inorganic Chemistry;Cross-Coupling;Phosphine Ligands;Phosphorus Compounds
Mol File:58656-04-5.mol
TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE Structure
TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE Chemical Properties
Melting point 164 °C(lit.)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Dichloromethane (Slightly), Methanol (Slightly)
form Powder
color White
Water Solubility Soluble in water.
InChIKeyKZGFMSRKDNYVKL-UHFFFAOYSA-N
Safety Information
Risk Statements 36/37/38
Safety Statements 22-24/25
RIDADR 1759
WGK Germany 3
TSCA No
HazardClass 8
PackingGroup III
HS Code 29209090
MSDS Information
ProviderLanguage
SigmaAldrich English
TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE Usage And Synthesis
ReactionsNon-pyrophoric, air-stable derivative suitable as a replacement for the neat phosphine in a variety of stoichiometric and catalytic processes.
Chemical PropertiesWhite powder
UsesTricyclohexylphosphine tetrafluoroborate may be used in the following processes:
  • As a ligand for preparing C-homoaporphine alkaloids via microwave-assisted direct-arylation.
  • To synthesize poly-[9,9-bis(3-propylamide-2-methylpropyl sulfonic acid) fluorene]-co-(4,4′-diphenyl) (PFDBSO3H), which can be employed as a template and doping agent for enhancing the conductivity of poly(3,4-ethylenedioxythiophene) (PEDOT) films.
  • To improve the reactivity of palladium-catalyzed Suzuki-Miyaura cross-coupling reaction between MIDA boronates and less activated alkenyl tosylates.
Usessuzuki reaction
UsesTricyclohexylphosphonium Tetrafluoroborate acts as a reagent in the synthesis of potent JAK2 inhibitor BMS-911543 as a potential treatment for myeloproliferative disorders, preparation of Lapatinib intermediate via arylation of furfural with bromochlorofluorobenzyloxyphenylquinazolinamine, structure-activity relationships of carboline and carbazole derivatives as ATP-competitive kinesin spindle protein inhibitors.
General DescriptionTricyclohexylphosphine tetrafluoroborate (PCy3·HBF4) is an inexpensive and air-stable phosphine ligand, commonly used in cross-coupling reactions.
TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE Preparation Products And Raw materials
N,N'-Dimethyl-1,2-ethanediamine Palladium (II) Acetate TRICYCLOPENTYLPHOSPHINE Lithium bis(trimethylsilyl)amide Tri-tert-butylphosphine tetrafluoroborate 1,3-Bis(diphenylphosphino)propane O-(2,2,2-Trifluoroethyl)hydroxylamine hydrochloride Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate Dichloromethane TRIS(1-PYRROLIDINYL)PHOSPHINE 97 N,N-Dimethylacetamide Tri-tert-butylphosphine CYCLOHEXYLPHOSPHINE BORANE-DICYCLOHEXYLPHOSPHINE COMPLEX TRIMETHYLPHOSPHONIUM TETRAFLUOROBORATE TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE TRIISOPROPYLPHOSPHONIUM TETRAFLUOROBORATE TRI-N-BUTYLPHOSPHONIUM TETRAFLUOROBORATE

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