(S)-(-)-1-(1-Naphthyl)ethylamine

(S)-(-)-1-(1-Naphthyl)ethylamine Basic information

Product Name:	(S)-(-)-1-(1-Naphthyl)ethylamine
Synonyms:	(1S)-1-NAPHTHALEN-1-YLETHANAMINE;(S)-(-)-1-(1-Naphthyl)ethylamine, ChiPros 99+%, ee 99+%;(S)-(-)-Alpha-(1-naphtyl)ethylamine, 99+%,;(-)-1-[(S)-1-Aminoethyl]naphthalene;(1S)-1-(1-Naphthyl)ethanamine;(S)-α-Methylnaphthalene-1-methanamine;(αS)-α-Methylnaphthalene-1-methanamine;[S,(-)]-α-Methyl-1-naphthalenemethanamine
CAS:	10420-89-0
MF:	C12H13N
MW:	171.24
EINECS:	600-536-0
Product Categories:	Miscellaneous;chiral;Amines (Chiral);Analytical Chemistry;Chiral Building Blocks;e.e. / Absolute Configuration Determination (NMR);Enantiomer Excess & Absolute Configuration Determination;for Resolution of Acids;Optical Resolution;Synthetic Organic Chemistry
Mol File:	10420-89-0.mol

(S)-(-)-1-(1-Naphthyl)ethylamine Chemical Properties

alpha	-60 º (C=2, MEOH)
Boiling point	153 °C/11 mmHg (lit.)
density	1.067 g/mL at 20 °C (lit.)
refractive index	n20/D 1.623(lit.)
Fp	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in chloroform, ethanol.
form	Liquid
pka	9.26±0.40(Predicted)
color	brown
optical activity	[α]20/D 59°, c = 5 in methanol
Sensitive	Air Sensitive
BRN	2208024
InChIKey	RTCUCQWIICFPOD-VIFPVBQESA-N
CAS DataBase Reference	10420-89-0(CAS DataBase Reference)
NIST Chemistry Reference	(S)-(-)-«alpha»-(1-naphthyl)ethylamine(10420-89-0)
EPA Substance Registry System	1-Naphthalenemethanamine, .alpha.-methyl-, (.alpha.S)- (10420-89-0)

Safety Information

MSDS Information

(S)-(-)-1-(1-Naphthyl)ethylamine Usage And Synthesis

Chemical Properties	Colorless to light yellow liqui
Uses	Employed in a preparation of a chiral thiourea solvating agent useful for enantiodiscrimination of α-hydroxy and α-amino acids by ¹H NMR.
Uses	(S)-(-)-1-(1-Naphthyl)ethylamine is used in the asymmetric synthesis of α-cyanocarboxylates. Also used in the synthesis of chiral imadazolin-2-ylidene ligands used in organometallic catalysis. Chiral/Asymmetric synthesis.
Uses	(S)-(-)-1-(1-Naphthyl)ethylamine is used in the asymmetric synthesis of α-cyanocarboxylates. Also used in the synthesis of chiral imadazolin-2-ylidene ligands used in organometallic catalysis. Chiral/ Asymmetric synthesis.
Purification Methods	Purify the amine by distillation in a good vacuum. [Mori et al. Tetrahedron 37 1343 1981, cf Wilson in Topics Stereochem (Allinger and Eliel eds) v o l 6 135 1971, Fredga et al. Acta Chem Scand 11 1609 1957.] The hydrochlorides crystallise from H2O [] D 18 ±3.9o (c 3, H2O), and the sulfates recrystallise from H2O as tetrahydrates m 230-232o. The RS-amine has b 153o/11mm, 156o/15mm, 183.5o/41mm [Blicke & Maxwell J Am Chem Soc 6 1 1780 1939]. [Beilstein 12 III 3111.]

(S)-(-)-1-(1-Naphthyl)ethylamine Preparation Products And Raw materials

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