ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Quinoline compounds 4-Chloro-7-(trifluoromethyl)quinoline

4-Chloro-7-(trifluoromethyl)quinoline

4-Chloro-7-(trifluoromethyl)quinoline Basic information
Product Name:4-Chloro-7-(trifluoromethyl)quinoline
Synonyms:BUTTPARK 15\09-27;Quinoline, 4-chloro-7-(trifluoromethyl)-;4-CHLORO-7-(TRIFLUOROMETHYL)QUINOLINE, 9 8%;4-Chloro-7-(trifluoromethyl)quinoline 98%;4-CHLORO-7-(TRIFLUOROMETHYL)QUINOLINE;4-Chloro-7-(trifluoroMethyl)quin;4-Chloro-7-(trifluoromethyl)quinoline ISO 9001：2015 REACH
CAS:346-55-4
MF:C10H5ClF3N
MW:231.6
EINECS:206-471-0
Product Categories:Quinoline&Isoquinoline;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Quinolines;QuinolinesHeterocyclic Building Blocks
Mol File:346-55-4.mol
4-Chloro-7-(trifluoromethyl)quinoline Structure
4-Chloro-7-(trifluoromethyl)quinoline Chemical Properties
Melting point 69-71 °C(lit.)
Boiling point 265.5±35.0 °C(Predicted)
density 1.4120 (estimate)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility chloroform: soluble25mg/mL, clear, colorless
pka1.18±0.27(Predicted)
form Solid
color Light Beige to Beige
CAS DataBase Reference346-55-4(CAS DataBase Reference)
NIST Chemistry Reference4-Chloro-7-(trifluoromethyl)quinoline(346-55-4)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 26-37/39-24/25
WGK Germany 3
HazardClass IRRITANT
HS Code 2933499090
MSDS Information
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4-Chloro-7-(trifluoromethyl)quinoline English
SigmaAldrich English
ACROS English
4-Chloro-7-(trifluoromethyl)quinoline Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses4-Chloro-7-(trifluoromethyl)quinoline is a reagent in the preparation of piperazinylquinolines as breast cancer inhibitors.
4-Chloro-7-(trifluoromethyl)quinoline Preparation Products And Raw materials
Raw materialsPhosphorus oxychloride-->Triethyl orthoformate-->Diethyl malonate-->Diphenyl ether-->3-Aminobenzotrifluoride
Preparation Products(Quinolin-7-yl)methanamin hydrochloride-->methyl 4-chloroquinoline-7-carboxylate
2-CHLORO-4-(TRIFLUOROMETHYL)QUINOLINE methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate ETHYL 4-CHLORO-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE 4-Chloro-7-trifluoromethyl-quinoline-3-carbonitrile OTAVA-BB 1088442 4-Bromo-8-chloro-2-(trifluoromethyl)quinoline 4-CHLORO-3-(TRIFLUOROMETHYL)QUINOLINE 2-CHLORO-3-(TRIFLUOROMETHYL)QUINOLINE 4-Chloro-7-(trifluoromethyl)quinoline 5,7-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE 4,6-DICHLORO-2-(TRIFLUOROMETHYL)QUINOLINE 8-BROMO-2-CHLORO-3-(TRIFLUOROMETHYL)QUINOLINE 4-CHLORO-2-METHYL-7-(TRIFLUOROMETHYL)QUINOLINE 4-BROMO-6-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE 5-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBOXYLIC ACID 4-CHLORO-6-TRIFLUOROMETHYL-QUINOLINE-3-CARBONITRILE 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLIC ETHYL ESTER 3-BROMO-4-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE
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