ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Methylpyridine 2-Chloro-5-trifluoromethylpyridine

2-Chloro-5-trifluoromethylpyridine

2-Chloro-5-trifluoromethylpyridine Basic information
Synthesis
Product Name:2-Chloro-5-trifluoromethylpyridine
Synonyms:2-choro-5-(trifluoromethyl) pyridine;2-chloro-5-(trifluoromethyl)-pyridin;2-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE;2,5-CTF;2 - chloro - 5-3 Methyl pyridine;5-CTF;2-chlorine-5-trifluoromethyl pyridine;oro-5-(trifL
CAS:52334-81-3
MF:C6H3ClF3N
MW:181.54
EINECS:257-856-5
Product Categories:Fluorine series;API Intermediate;Chloropyridines;Halopyridines;C6Heterocyclic Building Blocks;Halogenated Heterocycles;blocks;FluoroCompounds;Pyridines;Pyridines, Pyrimidines, Purines and Pteredines;Pyridine series;Halides;Pyridines derivates;Heterocyclic Building Blocks;Pyridine;bc0001
Mol File:52334-81-3.mol
2-Chloro-5-trifluoromethylpyridine Structure
2-Chloro-5-trifluoromethylpyridine Chemical Properties
Melting point 32-34 °C(lit.)
Boiling point 152 °C
density 1.417 g/mL at 25 °C(lit.)
Fp >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Crystalline Low Melting Solid
pka-2.57±0.10(Predicted)
Specific Gravity1.417
color White to yellow
BRN 3649688
InChIKeyJFZJMSDDOOAOIV-UHFFFAOYSA-N
CAS DataBase Reference52334-81-3(CAS DataBase Reference)
EPA Substance Registry SystemPyridine, 2-chloro-5-(trifluoromethyl)- (52334-81-3)
Safety Information
Hazard Codes Xi,Xn,T,F
Risk Statements 36/37/38-20/21/22-25-11
Safety Statements 26-37/39-36/37/39-45-22-16
RIDADR 2811
WGK Germany 3
RTECS US7530000
Hazard Note Irritant
TSCA T
HazardClass 6.1
PackingGroup III
HS Code 29339900
MSDS Information
ProviderLanguage
2,5-CTF English
ACROS English
SigmaAldrich English
ALFA English
2-Chloro-5-trifluoromethylpyridine Usage And Synthesis
Synthesis2-Chloro-5-trifluoromethylpyridine can be synthesized by fluorination of 2-chloro-5-trichloromethylpyridine.
Chemical Propertieswhite to yellowish crystalline low melting solid
Uses2-Chloro-5-(trifluoromethyl)pyridine may be employed as model substrate to investigate the regioexhaustive functionalization.
General Description2-Chloro-5-(trifluoromethyl)pyridine is a chloro(trifluoromethyl) pyridine.
3-Trifluoromethylpyridine (Trifluoromethyl)trimethylsilane 4-(Trifluoromethyl)pyridine 2-Chloro-6-(trifluoromethyl)pyridine 3-(Trifluoromethyl)benzaldehyde 2-Chloro-5-chloromethylpyridine 4-Methylpyridine 3-（trifluoromethyl) Cinnamaldehyde 2-Chloro-3-(trifluoromethyl)pyridine Difluorochloromethane Azamethiphos 2,4,6-Collidine Chloromethyltrimethylsilane 2-Chloro-5-trichloromethylpyridine 2-Chloro-4-(trifluoromethyl)pyridine 2-(Trifluoromethyl)pyridine Pyridine 2-Chloro-5-methylpyridine
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