CRUFOMATE

CRUFOMATE Basic information
Product Name:CRUFOMATE
Synonyms:RUELENE (TM);MONTREL;crufomate (bsi,iso,ansi);4-TERT-BUTYL-2-CHLOROPHENYLMETHYLMETHYLPHOSPHORAMIDE;(4-tetra-Butyl-2-chlorophenylmethyl methylphosphoramidate;crufomat (ISO) 4-tert-butyl-2-chlorophenyl methyl methylphosphoramidate;DOWCO 132;ENT 25602-X
CAS:299-86-5
MF:C12H19ClNO3P
MW:291.71
EINECS:206-083-1
Product Categories:
Mol File:299-86-5.mol
CRUFOMATE Structure
CRUFOMATE Chemical Properties
Melting point 60℃
Boiling point bp0.01 117-118°
density 1.176
refractive index nD20 1.5142
form solid
pka0.05±0.70(Predicted)
Water Solubility 4.975g/L(temperature not stated)
EPA Substance Registry SystemCrufomate (299-86-5)
Safety Information
Hazard Codes Xn,N
Risk Statements 21/22-50/53
Safety Statements 36/37-60-61
RIDADR UN2783 (solid)
HS Code 29299090
Hazardous Substances Data299-86-5(Hazardous Substances Data)
ToxicityLD50 in male, female rats (mg/kg): 635, 460 orally (Gaines)
MSDS Information
CRUFOMATE Usage And Synthesis
Chemical PropertiesCrufomate is a white crystalline solid; the commercial product is a yellow oil.
UsesSystemic insecticide and anthelmintic.
UsesCrufomate is an organophosphate pesticide. Crufomate is an anthelmintic that functions as a potent inhibitor of an acetylcholinesterase in the anterior end of the worms. Crufomate is also used to combat bovine hypodermatosis.
UsesCrufomate is an organophosphate pesticide. Crufomate is an anthelmintic that functions as a potent inhibitor of an acetylcholinesterase in the anterior end of the worms. Crufomate is also used to comb at bovine hypodermatosis.
DefinitionChEBI: Crufomate is an alkylbenzene.
General DescriptionWhite crystalline solid Mp: 61.5°C. The commercial product is a yellow oil. A phosphoramidate insecticide.
Reactivity ProfileCRUFOMATE is combustible; liquid formulations containing organic solvents may be flammable. Incompatible with strongly basic and strongly acidic materials. Unstable over long periods in aqueous preparations or above140°F. Emits toxic fumes of POx, Cl2 and NOx when heated to decomposition (Hazardous Chemicals Desk Reference p. 272 (1987)).
HazardCholinesterase inhibitor. Questionable carcinogen.
Agricultural UsesInsecticide, Anthelmintic (for cattle): All residue limits for crufomate, as listed in 40 CFR 180.295, were revoked by the U.S. EPA on June 9, 1993. All registered uses of crufomate in or on fat, meat, and meat byproducts of cattle, goats, and sheep were canceled It is applied as a spray on plants to kill insects, grubs, and worms on cattle. Not listed for use in EU countries
Trade nameDOWCO® 132[C]; MONTREL®[C]; RUELENE®[C]; DRENCH®[C]; RULENE®[C]
Potential ExposureA potential danger to those involved in the manufacture, formulation, and application of this insecticide and anthelmintic for cattle.
ShippingUN2783 Organophosphorus pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
IncompatibilitiesContact with oxidizers may cause the release of phosphorous oxides. Contact with strong reducing agents, such as hydrides, may cause the formation of flammable and toxic phosphine gas. Decomposes on heating, forming corrosive and toxic fumes of hydrogen chloride and nitrogen and phosphorous oxides. Incompatible with strongly alkaline and strongly acidic media. Unstable over long periods in aqueous preparations or above 60°C.
Waste DisposalCrufomate decomposes above pH 7.0 in alkaline media. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office
CRUFOMATE Preparation Products And Raw materials
Phoxim Phosmet Metasystox TRIMETHYLPHOSPHORAMIDE 4-tert-Butyl-2-chlorophenol CRUFOMATE

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