( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester )

( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester ) Basic information
Product Name:( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester )
Synonyms:( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester );4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]-1-butanol;[4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]butoxy]acetic acid 1,1-dimethylethyl ester;TUQMNTRUQSTQNJ-UHFFFAOYSA-N;Selexipag Impurity 8;tert-butyl 2-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)acetate;Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-, 1,1-dimethylethyl ester;1,1-Dimethylethyl 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]acetate
CAS:475084-96-9
MF:C29H37N3O3
MW:475.62
EINECS:
Product Categories:
Mol File:475084-96-9.mol
( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester ) Structure
( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester ) Chemical Properties
Boiling point 592.3±50.0 °C(Predicted)
density 1.090±0.06 g/cm3(Predicted)
pka2.40±0.10(Predicted)
Safety Information
MSDS Information
( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester ) Usage And Synthesis
Uses2-{4-[N-(5,6-Diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butyl ester is an impurity of Selexipag (S253150), an orally available, highly selective, long-acting prostacyclin (IP) receptor agonist prodrug. It is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.
( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester ) Preparation Products And Raw materials
Acetamide, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]- 5-chloro-2,3-diphenylpyrazine Acetamide, 2-[4-[(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)- [4-[(5,6-DIPHENYLPYRAZINYL)(1-METHYLETHYL)AMINO]BUTOXY]-ACETIC ACID SELEXIPAG interMediate Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]-, 1,1-dimethylethyl ester 4-(Isopropylamino)butanol 2-T-BUTYL GLYCOLATE Bromoacetic acid 2,3-DIPHENYLPYRAZINE 1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)oxy]- 2,3-Dichloro-5,6-diphenylpyrazine N-(methylsulfonyl)glycine 5,6-DIPHENYLPYRAZIN-2-OL 2-Pyrazinamine, N-(1-methylethyl)-5,6-diphenyl- Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]-

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