tert-Butyl O,O-dimethylphosphonoacetate

tert-Butyl O,O-dimethylphosphonoacetate Basic information
Product Name:tert-Butyl O,O-dimethylphosphonoacetate
Synonyms:tert-Butyl P,P-diMethylphosphonoacetate, >= 97.0 % GC;tert-Butyl ((oxo)dimethoxyphosphino)acetate;tert-Butyl (dimethoxyphosphinyl)acetate;tert-Butyl 2-(dimethoxyphosphoryl);Tert-butyl dimethylphosphonoactate;Dimethyl (Boc-methyl)phosphonate;TERT-BUTYL P,P-DIMETHYLPHOSPHONOACETATE;tert-Butyl O,O-dimethylphosphonoacetate
CAS:62327-21-3
MF:C8H17O5P
MW:224.19
EINECS:
Product Categories:
Mol File:62327-21-3.mol
tert-Butyl O,O-dimethylphosphonoacetate Structure
tert-Butyl O,O-dimethylphosphonoacetate Chemical Properties
Boiling point 86-87 °C0.02 mm Hg(lit.)
density 1.131 g/mL at 20 °C(lit.)
refractive index n20/D 1.434
Fp 110 ºC
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form clear liquid
color Colorless to Almost colorless
BRN 4861886
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
9-23
HS Code 2931.39.0030
MSDS Information
ProviderLanguage
SigmaAldrich English
tert-Butyl O,O-dimethylphosphonoacetate Usage And Synthesis
UsesReactant for:
  • Preparation of phosphonate terminated PPH dendrimers as anti-HIV-1 agents
  • Preparation of monodehydro diketopiperazines from ketoacyl amino acid amides via acid-catalyzed cyclization
  • Preparation of α,β-unsaturated esters for use in the guanidine-catalyzed oxa-Michael addition
  • Preparation of myxopyronin B and desmethyl myxopyronin B analogs, with antibacterial activity and inhibitory activity against bacterial RNA polymerase
  • Allylation and subsequent ring-closing metathesis in presence of Grubbs′ catalyst or intramolecular rhodium-catalyzed cyclopropanation reactions
tert-Butyl O,O-dimethylphosphonoacetate Preparation Products And Raw materials
Raw materialsTrimethyl phosphonoacetate-->Potassium tert-butoxide
Dacthal t-butyl chloroformate Cyhalofop-butyl Diphenyldimethoxysilane Dimethyldimethoxysilane ETHANE Buprofezin tert-Butanol Sodium lauroylglutamate Dimethyl sulfide Dimethyl fumarate Sodium lauroylsarcosinate BUTYL OLEATE Dimethyl sulfoxide Dimethyl ether tert-Butyl glycinate tert-Butyl carbazate Dimethyl sulfate

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