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| 2-Amino-3-picoline Basic information |
| 2-Amino-3-picoline Chemical Properties |
Melting point | 29-31 °C (lit.) | Boiling point | 221-222 °C (lit.) | density | 1.073 g/mL at 25 °C (lit.) | refractive index | n20/D 1.5823(lit.) | Fp | 233 °F | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | solubility | 1000g/l | form | Liquid After Melting | pka | pK1: 7.24(+1) (25°C) | color | Clear yellow | Water Solubility | SOLUBLE | Sensitive | Hygroscopic | BRN | 107892 | InChIKey | RGDQRXPEZUNWHX-UHFFFAOYSA-N | CAS DataBase Reference | 1603-40-3(CAS DataBase Reference) | NIST Chemistry Reference | 2-Pyridinamine, 3-methyl-(1603-40-3) | EPA Substance Registry System | 2-Pyridinamine, 3-methyl- (1603-40-3) |
| 2-Amino-3-picoline Usage And Synthesis |
Chemical Properties | 2-Amino-3-picoline is CLEAR YELLOW LIQUID AFTER MELTING
| Uses | 2-Amino-3-picoline is used in the synthesis of ketones from aldehydes.
| Synthesis Reference(s) | Journal of the American Chemical Society, 95, p. 4453, 1973 DOI: 10.1021/ja00794a070 | Hazard | Toxic by ingestion. | Purification Methods | Recrystallise the picoline three times from *benzene, most of the residual *benzene being removed from the crystals by standing over paraffin wax chips in an evacuated desiccator. The amine is also transferred to a separating funnel under N2, and left in contact with NaOH pellets for 3hours with occasional shaking. It is then placed in a vacuum distilling flask where it is refluxed gently in a stream of dry N2 before fractionally distilling it. [Mod et al. J Phys Chem 60 1651 1956, Beilstein 22/9 V 212]. |
| 2-Amino-3-picoline Preparation Products And Raw materials |
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