|
| | MOLLUGIN Basic information |
| | MOLLUGIN Chemical Properties |
| Melting point | 132～134℃ | | Boiling point | 453.2±45.0 °C(Predicted) | | density | 1.239±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | pka | 8.40±0.40(Predicted) | | form | Solid | | color | Yellow to Green |
| Safety Statements | 24/25 | | HS Code | 29329990 |
| | MOLLUGIN Usage And Synthesis |
| Uses | Mollugin is an anti-tumor agent inducing apoptosis and autophagy in various cancer models. | | Definition | ChEBI: Rubimaillin is a benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-kappaB activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme. It has a role as a plant metabolite, an acyl-CoA:cholesterol acyltransferase 2 inhibitor, a NF-kappaB inhibitor, an antineoplastic agent, an apoptosis inducer, a neuroprotective agent and an anti-inflammatory agent. It is a benzochromene, a methyl ester and a member of phenols. |
| | MOLLUGIN Preparation Products And Raw materials |
|
