ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Phenylalanine derivatives L-4-Chlorophenylalanine

L-4-Chlorophenylalanine

L-4-Chlorophenylalanine Basic information
Product Name:L-4-Chlorophenylalanine
Synonyms:3-(4-Chlorophenyl)-L-alanine;(2R)-2-amino-3-(4-chlorophenyl)propanoic acid;4-CHLORO-L-PHE-OH.HCL;4-Chloro-L-phenylalanine99+%;P-CHLORO-PHENYLALANINE;P-CHLORO-L-PHENYLALANINE;RARECHEM BK PT 0013;(S)-2-AMINO-3-(4-CHLORO-PHENYL)-PROPIONIC ACID
CAS:14173-39-8
MF:C9H10ClNO2
MW:199.63
EINECS:238-023-5
Product Categories:Phenylalanine analogs and other aromatic alpha amino acids;Amino Acids;a-amino;Phenylalanine [Phe, F];Unusual Amino Acids
Mol File:14173-39-8.mol
L-4-Chlorophenylalanine Structure
L-4-Chlorophenylalanine Chemical Properties
Melting point 263 °C (dec.)(lit.)
Boiling point 339.5±32.0 °C(Predicted)
alpha -27 º (c=0.5, H2O 34 ºC)
density 1.2409 (rough estimate)
refractive index 1.5790 (estimate)
storage temp. -20°C
solubility Aqueous Base (Slightly), Water (Slightly)
form Powder
pka2.18±0.10(Predicted)
color White
Water Solubility Soluble in acetic acid. Slightly soluble in water.
BRN 2416150
InChIKeyNIGWMJHCCYYCSF-QMMMGPOBSA-N
CAS DataBase Reference14173-39-8(CAS DataBase Reference)
Safety Information
Hazard Codes T,Xi
Risk Statements 25-43
Safety Statements 36/37-45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
HazardClass 6.1
PackingGroup Ⅲ
HS Code 29224999
MSDS Information
ProviderLanguage
L-4-Chlorophenylalanine English
SigmaAldrich English
ACROS English
L-4-Chlorophenylalanine Usage And Synthesis
Chemical Propertieswhite powder
Uses4-Chloro-L-phenylalanine is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals.
DefinitionChEBI: A non-proteinogenic L-alpha-amino acid that is L-phenylalanine in which the meta-hydrogen of the phenyl group has been replaced by a chlorine.
Biochem/physiol Actions4-Chloro-L-phenylalanine (L-PCPA) inhibits the synthesis of 5-hydroxytryptamine (5-HT). 4-Chloro-DL-phenylalanine (PCPA) depletes the serotonin levels in the brain by its inhibitory effect on tryptophan hydroxylase (Tph). Studies support the protective effects of PCPA against monocrotaline-induced pulmonary vascular remodeling as well as in lung inflammation.
L-4-Chlorophenylalanine Preparation Products And Raw materials
Preparation ProductsDL-4-Chlorophenylalanine
3,4-Dichlorophenylalanine Phenprobamate FMOC-DL-4-CHLOROPHENYLALANINE FMOC-L-4-CHLOROPHENYLALANINE,(S)-N-FMOC-4-CHLOROPHENYLALANINE tert-butoxycarbonyl-l-4-chlorophenylalanine,(S)-N-BOC-4-CHLOROPHENYLALANINE Boc-beta-(S)-4-chlorophenylalanine,Boc-(S)-4-Chlorophenylalanine P-CHLOROPHENYLALANINE METHYLESTER HYDROCHLORIDE,L-4-CHLOROPHENYLALANINE METHYL ESTER HCL DL-4-Chlorophenylalanine methyl ester hydrochloride FMOC-L-Β-CHLORO-ALA-OH, 2-CHLOROPHENYLALANINE [PHE(2-CL)] PHENYL RESIN EC 2.6.1.2 (R)-N-FMOC-4-CHLOROPHENYLALANINE,FMOC-D-4-CHLOROPHENYLALANINE L-Alanine PHENYL VALERATE Fmoc-beta-(R)-4-chlorophenylalanine BOC-D-3,4-Dichlorophe BOC-L-3,4-Dichlorophe CHLOROPHENYLALANINE
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