ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Piperazine compounds (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid

(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid

(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid Basic information
Product Name:(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid
Synonyms:(R)-(-)-ALPHA-[[(4-ETHYL-2,3-DIOXO-1-PIPERAZINYL)CARBONYL]AMINO]-4-HYDROXYBENZENEACETIC ACID;(R)-(-)-[[(4-ETHYL-2,3-DIOXO-1-PIPERAZINYL)CARBONYL]AMINO]-4-HYDROXYBENZENEACETIC ACID;D-(-)-A-(4-ETHYL-2,3-DIOXO PIPERZINYL) CARBOCAMIDE-4-HYDROXYPHENYL-ACETIC ACID;D-(-)-2-(2,3-DIOXO-4-ETHYL-1-PIPERAZIN-CARBOXAMIDE)-ALPHA-4-HYDROXY PHENYL ACETIC ACID;D-(-)-2-[(4-ETHYL-2,3-DIOXO-1-PIPERAZINEYL)-CARBONYLAMINO]-2-(4-HYDROXYPHENYL) ACETIC ACID;2R-2-((4-ETHYL-2,3-DIOXYPIPERAZYL)FORMAMIDE)-P-HYDROXY PHENYLACETIC ACID;(2R)-2-[(4-ETHYL-2,3-DIOXOPIPERAZINYL)CARBONYLAMINO]-2-(4-HYDROXYPHENYL)ACETIC ACID;N-((4-ETHYL-2,3-DIOXO-1-PIPERAZINYL)CARBONYL)-A-AMINO-P- HYDROXYPHENYLACETIC ACID
CAS:62893-24-7
MF:C15H17N3O6
MW:335.32
EINECS:625-629-3
Product Categories:Chiral Building Blocks;Heterocyclic Building Blocks;Piperazines
Mol File:62893-24-7.mol
(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid Structure
(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid Chemical Properties
Melting point 205 °C (dec.) (lit.)
alpha -0.85 º(c=1,MeOH)
Boiling point 471.96°C (rough estimate)
density 1.2546 (rough estimate)
refractive index 1.5600 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Sparingly)
form Solid
pka3.40±0.10(Predicted)
color White to Off-White
optical activity[α]20/D 85°, c = 1 in methanol
CAS DataBase Reference62893-24-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
HS Code 2933.59.8000
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid Usage And Synthesis
Chemical Propertieswhite crystalline powder
Uses(αR)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneacetic Acid is an intermediate used to prepare Cephalosporin derivatives with activities against both Gram-positive and Gram-negative bacteria.
(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid Preparation Products And Raw materials
Raw materialsEthyl acetate-->Dichloromethane-->Sodium sulfate-->Sodium chloride-->Acetone-->1-Butanol-->Chlorotrimethylsilane-->Hexamethyldisilazane-->4-Hydroxy-D-(-)-2-phenylglycine-->4-Ethyl-2,3-dioxo-1-piperazine carbonyl chloride
{[(4-Ethyl-2,3-Dioxo-1-Piperazinyl) Carbonyl]Amino}-4-Hydroxy-Benzene Acetic Acid PIPERAZINE CITRATE HYDRATE Piperacillin Trinexapac-ethyl Ethanol DL-4-HYDROXYPHENYLGLYCINE (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid 3-Diethylaminophenol 1-Ethyl-2,3-dioxopiperazine 1-Hydroxyethylidene-1,1-diphosphonic acid Ethylparaben ISOXADIFEN-ETHYL Ethyl acetate PIPERAZINE-2,3-DIONE Ethyl propiolate Ethyl acrylate SALOR-INT L169811-1EA Ethyl cyanoacetate
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