(3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

(3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Basic information
Product Name:(3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
Synonyms:(3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one;Ezetimibe impurity 7;KETOROLAC BROMO IMPURITY;Ezetimibe Impurity 31;Ezetimibe Impurity G;N-Des(4-Fluorophenyl)-N-(3-fluorophenyl) Ezetimibe;Ezetimibe meta-Fluoroaniline Analog (USP);3-Fluoro Ezetimibe
CAS:1700622-06-5
MF:C24H21F2NO3
MW:409.43
EINECS:
Product Categories:ZJ
Mol File:1700622-06-5.mol
(3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Structure
(3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Chemical Properties
Boiling point 652.9±55.0 °C(Predicted)
density 1.334±0.06 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
pka9.72±0.30(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
(3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Usage And Synthesis
UsesN-Des(4-Fluorophenyl)-N-(3-fluorophenyl)-ezetimibe is a derivative of Ezetimibe (E975000), which is an antihyperlipoproteinemic and a cholesterol absorption inhibitor.
(3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Preparation Products And Raw materials
5-(4-FLUOROPHENYL)VALERIC ACID ent-EzetiMibe EzetiMibe (3R,4R,3'S)-IsoMer (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (3R,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (4S)-3-(2,2-dimethylpropanoyl)-4-phenyl-1,3-oxazolidin-2-one 4-BENZOYLBUTYRIC ACID 5-(2-FLUOROPHENYL)-5-OXOVALERIC ACID 3-O-Acetyl Ezetimibe Ezetimibe Impurity 72 N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline Ezetimibe Impurity 38 Ezetimibe Impurity 79 Ezetimibe Impurity (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone EzetiMibe Fluoro IsoMer EzetiMibe LactaM Cleaved Alcohol

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