RONIDAZOLE

RONIDAZOLE Basic information
Brand Name(s)
Product Name:RONIDAZOLE
Synonyms:1-METHYL-2-[CARBAMOYLOXYMETHYL]-5-NITROIMIDAZOLE;TIMTEC-BB SBB006916;RONIDAZOL;RONIDAZOLE;1-methyl-5-nitro-1h-imidazole-2-methanocarbamate(ester);1-methyl-5-nitro-1h-imidazole-2-methanolcarbamateester;1-methyl-5-nitro-imidazole-2-methanocarbamate(ester);dugro
CAS:7681-76-7
MF:C6H8N4O4
MW:200.15
EINECS:231-675-1
Product Categories:ANCEF;Amines;Heteroyclces;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:7681-76-7.mol
RONIDAZOLE Structure
RONIDAZOLE Chemical Properties
Melting point 167-169°
Boiling point 337.86°C (rough estimate)
density 1.5359 (rough estimate)
refractive index 1.6500 (estimate)
storage temp. −20°C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka1.2(at 25℃)
form neat
color Pale Yellow
InChIInChI=1S/C6H8N4O4/c1-9-4(3-14-6(7)11)8-2-5(9)10(12)13/h2H,3H2,1H3,(H2,7,11)
InChIKeyPQFRTXSWDXZRRS-UHFFFAOYSA-N
SMILESC1(COC(=O)N)=NC=C([N+]([O-])=O)N1C
Safety Information
Safety Statements 22-24/25
WGK Germany 2
RTECS NI6803000
HS Code 29332900
MSDS Information
ProviderLanguage
SigmaAldrich English
RONIDAZOLE Usage And Synthesis
Brand Name(s)Flagyl and generic
UsesAntimicrobial.
Usesantibacterial
DefinitionChEBI: Ronidazole is a carbamate ester that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by methyl and (carbamoyloxy)methyl groups, respectively. An antiprotozoal agent, it is used in veterinary medicine for the treatment of histomoniasis and swine dysentery. It has a role as an antiprotozoal drug and an antiparasitic agent. It is a member of imidazoles, a carbamate ester and a C-nitro compound.
Veterinary Drugs and TreatmentsRonidazole is a nitroimidazole antibiotic/antiparasitic drug that appears to be useful in treating Tritrichomonas foetus infections in cats. The drug is not commercially available in the USA and must be compounded from bulk powder by a compounding pharmacy. The drug is also used for treating Trichomonas infections in nonfood animal birds.
RONIDAZOLE Preparation Products And Raw materials
Raw materials1-Methyl-5-nitro-1H-imidazole-2-methanol
methylol cellulose Pyrimethanil Nitazoxanide alpha,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol Cefmetazole 2-Methyl-4-nitroimidazole 1H-IMIDAZOL-2-YLMETHANOL HYDROCHLORIDE (1-Methyl-1H-imidazol-2-yl)methanol 2-CARBAMOYLOXYMETHYL-1-METHYL-D3-5-NITRO-1H-IMIDAZOLE(RONIDAZOLE-D3) 1,2-Dimethyl-5-nitroimidazole Acetamide RONIDAZOLE (-)-MENTHYL CHLOROFORMATE 1-Methyl-5-nitro-1H-imidazole-2-methanol 1-METHYL-5-NITROIMIDAZOLE Ronidazole-d3 2-CARBAMOYLOXYMETHYL-1-METHYL-5-NITRO-1H-IMIDAZOLE(RONIDAZOLE)

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