Ezetimibe Impurity

Ezetimibe Impurity Basic information
Product Name:Ezetimibe Impurity
Synonyms:Ezetimibe IMP;(R)-N,5-bis(4-fluorophenyl)-2-(4- hydroxybenzyl)pentanamide;(2R,3R,6S)-6-(4-fluorophenyl)-2-(4-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran-3-carboxylic acid;N,5-Bis(4-fluorophenyl)-2R-(4-hydroxybenzyl)pentanamide;Benzenepentanamide, 4-fluoro-N-(4-fluorophenyl)-α-[(4-hydroxyphenyl)methyl]-, (αR)-;3-Dehydroxy Ezetimibe Open Ring Impurity;Ezetimibe-11;Ezetimibe impuriry 13/(R)-N,5-bis(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide
CAS:1510820-22-0
MF:C24H23F2NO2
MW:395.45
EINECS:
Product Categories:
Mol File:1510820-22-0.mol
Ezetimibe Impurity Structure
Ezetimibe Impurity Chemical Properties
Boiling point 610.4±55.0 °C(Predicted)
density 1.246±0.06 g/cm3(Predicted)
solubility Dichloromethane; DMSO; Ethyl Acetate
form Solid
pka10.04±0.15(Predicted)
color White
Safety Information
MSDS Information
Ezetimibe Impurity Usage And Synthesis
Uses3-Dehydroxy Ezetimibe Open Ring Impurity is an impurity in the synthesis of 3-Dehydroxy Ezetimibe, a derivative of Ezetimibe (E975000), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.
Ezetimibe Impurity Preparation Products And Raw materials
ent-EzetiMibe EzetiMibe Fluoro IsoMer (S)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one 5-(3-FLUOROPHENYL)-5-OXOVALERIC ACID Ezetimibe Impurity 45 Benzenepentanoic acid, 4-fluoro-δ-oxo-, anhydride with 2,2-dimethylpropanoic acid Tenofovir disoproxil fumarate (αR,δS)-4-Fluoro-N-(4-fluorophenyl)-δ-hydroxy-α-[(4-hydroxyphenyl)Methyl]benzenepentanaMide (3S,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one 3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl(amino)]][4-[trimethylsilyl]-oxy]phenyl]methyl]-1-oxo-5-[(trimethylsily)-oxy]pentyl]-4-phenyl-(4S)-2-oxazolidinone Ezetimibe Impurity 71 Ezetimibe-28 (R)-(-)-4-Phenyl-2-oxazolidinone EzetiMibe Azetidinone Ring-opened IMpurity EzetiMibe IMpurity 1 Ezetimibe (RSS)-Isomer Ezetimibe Impurity 35 Ezetimibe Impurity 78

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