Cinacalcet IMpurity 9

Cinacalcet IMpurity 9 Basic information
Product Name:Cinacalcet IMpurity 9
Synonyms:Cinacalcet IMpurity 9;(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine;Cinacalcet impurity 13/Cinacalcet Dihydro Impurity 2 HCl/(R)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl) phenyl)propan-1-amine hydrochloride;Cinacalcet-13;(R)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-;N-[(1R)-1-(5,6-dihydronaphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;N-(1-(7,8-dihydrophthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-aminehydrochloride;Cinacalcet Dihydro Impurity 2 HCl
CAS:802918-36-1
MF:C22H24F3N
MW:359.44
EINECS:
Product Categories:
Mol File:802918-36-1.mol
Cinacalcet IMpurity 9 Structure
Cinacalcet IMpurity 9 Chemical Properties
Boiling point 433.5±45.0 °C(Predicted)
density 1.138±0.06 g/cm3(Predicted)
pka9.46±0.29(Predicted)
Safety Information
MSDS Information
Cinacalcet IMpurity 9 Usage And Synthesis
Uses(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is synthetically prepared though a double bond migration in Heck reaction during the preparation of cinacalcet congeners. This enantiomerically pure material is seperated from its counter part, (αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (D455330) using HPLC.
Cinacalcet IMpurity 9 Preparation Products And Raw materials
Cinacalcet Impurity B Cinacalcet Impurity H 1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethan-1-amine hydrochloride N-(1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide Cinacalcet IMpurity 3 (E)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)acrylamide Cinacalcet impurity C Cinacalcene Impurity I 1-(7,8-dihydronaphthalen-1-yl)ethan-1-amine hydrochloride 1-NaphthaleneMethanaMine, 7,8-dihydro-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)- N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide cinacalcet iMpurity 8 Cinacalcet Impurity 21 (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoroMethyl)phenyl)propan-1-aMine Cinacalcet Impurity A Cinacalcet impurity G Cinacalcet IMpurity 6 Cinacalcet Impurity 22

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